CAS 74815-57-9
:gastrin releasing peptide
Description:
Gastrin-releasing peptide (GRP), with the CAS number 74815-57-9, is a neuropeptide that plays a crucial role in various physiological processes, particularly in the gastrointestinal system. It is a member of the bombesin-like peptide family and is primarily involved in stimulating the release of gastrin, a hormone that promotes gastric acid secretion. GRP is composed of a chain of amino acids, typically consisting of 27 residues, and is synthesized in the central nervous system and gastrointestinal tract. This peptide is known for its role in regulating appetite, influencing smooth muscle contraction, and modulating the release of other gastrointestinal hormones. GRP also has implications in neurobiology, as it can act as a neurotransmitter or neuromodulator. Its biological activity is mediated through specific receptors, primarily the bombesin receptor subtype 1. Due to its diverse functions, GRP is of interest in research related to digestive disorders, cancer, and neurodevelopmental conditions.
Formula:C126H198N38O31S2
InChI:InChI=1/C126H198N38O31S2/c1-62(2)44-83(155-121(191)102(67(11)12)162-123(193)103(71(16)166)158-98(173)56-138-94(169)54-137-95(170)55-140-120(190)100(65(7)8)160-116(186)90(59-165)157-122(192)101(66(9)10)161-118(188)92-31-24-40-163(92)124(194)68(13)128)110(180)144-69(14)105(175)149-81(28-21-22-38-127)108(178)150-82(37-43-197-18)109(179)156-89(46-72-32-34-76(167)35-33-72)125(195)164-41-25-30-91(164)117(187)151-80(29-23-39-135-126(131)132)107(177)139-57-96(171)147-88(50-93(129)168)115(185)154-87(49-75-53-134-61-143-75)114(184)153-85(47-73-51-136-78-27-20-19-26-77(73)78)111(181)145-70(15)106(176)159-99(64(5)6)119(189)141-58-97(172)146-86(48-74-52-133-60-142-74)113(183)152-84(45-63(3)4)112(182)148-79(104(130)174)36-42-196-17/h19-20,26-27,32-35,51-53,60-71,79-92,99-103,136,165-167H,21-25,28-31,36-50,54-59,127-128H2,1-18H3,(H2,129,168)(H2,130,174)(H,133,142)(H,134,143)(H,137,170)(H,138,169)(H,139,177)(H,140,190)(H,141,189)(H,144,180)(H,145,181)(H,146,172)(H,147,171)(H,148,182)(H,149,175)(H,150,178)(H,151,187)(H,152,183)(H,153,184)(H,154,185)(H,155,191)(H,156,179)(H,157,192)(H,158,173)(H,159,176)(H,160,186)(H,161,188)(H,162,193)(H4,131,132,135)/t68-,69-,70-,71+,79-,80-,81-,82-,83-,84-,85-,86-,87-,88-,89-,90-,91-,92-,99-,100-,101-,102-,103-/m0/s1
Synonyms:- Gastrin-releasing peptide (pig)
- Gastrin Releasing Peptide, Porcine
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Found 1 products.
GRP (porcine)
CAS:GRP: agonist for GRPR, stimulates amygdala GABA release reducing fear in mice, aids mitogenesis, GI function, and appetite control.Formula:C126H198N38O31S2Purity:98%Color and Shape:SolidMolecular weight:2805.31
