CAS 74817-61-1

Murabutide

Description:

Murabutide, with the CAS number 74817-61-1, is a synthetic compound that serves as a potent immunomodulator. It is primarily recognized for its role as a ligand for Toll-like receptor 2 (TLR2), which is part of the innate immune system. This interaction stimulates immune responses, making Murabutide of interest in research related to immunotherapy and vaccine development. The compound is characterized by its ability to enhance the activity of immune cells, such as macrophages and dendritic cells, thereby promoting the production of pro-inflammatory cytokines. Murabutide is typically studied in the context of its potential therapeutic applications in infectious diseases and cancer, where modulation of the immune response can be beneficial. Additionally, its chemical structure includes specific functional groups that contribute to its biological activity, although detailed structural information is not provided here. Overall, Murabutide represents a significant area of interest in pharmacological research due to its immunostimulatory properties.

Formula: C₂₃H₄₀N₄O₁₁

InChI: InChI=1/C23H40N4O11/c1-5-6-9-36-22(34)14(7-8-16(24)30)27-20(32)11(2)25-21(33)12(3)37-19-17(26-13(4)29)23(35)38-15(10-28)18(19)31/h11-12,14-15,17-19,23,28,31,35H,5-10H2,1-4H3,(H2,24,30)(H,25,33)(H,26,29)(H,27,32)/t11-,12+,14+,15+,17+,18+,19+,23?/m0/s1

Synonyms:

• Murabutide [INN]
• N-Acetylmuramyl-alanylglutamine-n-butyl ester
• 2-Acetamido-3-O-((R)-1-(((S)-1-(((R)-3-carbamoyl-1-carboxypropyl)carbamoyl)ethyl)carbamoyl)ethyl)-2-deoxy-D-glucopyranose, butyl ester
• Butyl N2-((2S)-2-((2R)-2-(2-acetamido-2-desoxy-D-3-glucopyranosyloxy)propionamido)propionyl)-D-glutaminat
• Murabutida
• Murabutida [Spanish]
• Murabutidum
• Murabutidum [Latin]
• D-Glutamine, N2-(N-(N-acetylmuramoyl)-L-alanyl)-, butyl ester
• butyl (2R)-2-{[(2R)-2-{[(2S)-2-{[3-(acetylamino)-2,5-dihydroxy-6-(hydroxymethyl)tetrahydro-2H-pyran-4-yl]oxy}propanoyl]amino}propanoyl]amino}-5-amino-5-oxopentanoate (non-preferred name)
• butyl (2R)-2-{[(2R)-2-{[(2S)-2-{[(3S,4S,5R,6S)-3-(acetylamino)-2,5-dihydroxy-6-(hydroxymethyl)tetrahydro-2H-pyran-4-yl]oxy}propanoyl]amino}propanoyl]amino}-5-amino-5-oxopentanoate (non-preferred name)

Murabutide

CAS: 74817-61-1

Murabutide is an HIV drug that belongs to the class of protease inhibitors. It is a competitive inhibitor of HIV-1 protease, which blocks the cleavage of polypeptides and inhibits viral replication. Murabutide has been shown to be active against both wild-type and drug-resistant strains of HIV-1 in cell culture studies. This agent exhibits low toxicity in animals, with minimal effects on weight gain and food consumption, as well as no significant changes in hematology or serum chemistry values. Murabutide also has minimal effects on human macrophages and human immunoglobulin levels. In addition, murabutide has shown minimal toxicity in animal models, with no significant changes in weight gain or food consumption and no significant changes in hematology or serum chemistry values. Murabutide also has minimal effects on human macrophages and human immunoglobulin levels.

Purity: Min. 95%

Ref: 3D-FM177896

Murabutide

CAS: 74817-61-1

Murabutide, a safe synthetic immunomodulator, diminishes the expression of CD4 and CCR5 receptors and promotes the secretion of high levels of beta-chemokines,

Formula: C₂₃H₄₀N₄O₁₁

Color and Shape: Solid

Molecular weight: 548.58

Ref: TM-T81738