CAS 74843-14-4

16(S)-Iloprost

Description:

16(S)-Iloprost is a synthetic analog of prostacyclin (PGI2), a potent vasodilator and inhibitor of platelet aggregation. It is characterized by its ability to mimic the effects of natural prostacyclin, making it useful in various therapeutic applications, particularly in the treatment of pulmonary arterial hypertension and peripheral vascular diseases. The compound exhibits a high affinity for prostacyclin receptors, leading to vasodilation and inhibition of platelet aggregation. Its chemical structure includes a bicyclic ring system with multiple functional groups that contribute to its biological activity. 16(S)-Iloprost is typically administered via inhalation or intravenous routes, allowing for rapid onset of action. The substance is known for its relatively short half-life, necessitating continuous or frequent dosing in clinical settings. Additionally, it may cause side effects such as flushing, headache, and gastrointestinal disturbances, which are common with prostacyclin analogs. Overall, 16(S)-Iloprost represents a significant advancement in the management of conditions associated with impaired blood flow and vascular function.

Formula: C₂₂H₃₂O₄

Synonyms:

• Pentanoic acid, 5-[(3aS,4R,5R,6aS)-hexahydro-5-hydroxy-4-[(1E,3S,4S)-3-hydroxy-4-methyl-1-octen-6-yn-1-yl]-2(1H)-pentalenylidene]-, (5E)-
• 16(S)-Iloprost
• HIFJCPQKFCZDDL-ITQKTNNISA-N

16-(S)-Iloprost

CAS: 74843-14-4

Formula: C₂₂H₃₂O₄

Molecular weight: 360.49

Ref: 4Z-I-098003

16-(S)-Iloprost

CAS: 74843-14-4

Applications 16-(S)-Iloprost is the S-isomer of Iloprost (I267300), a synthetic analogue of Prostacyclin (PGI2) used to treat pulmonary arterial hypertension (PAH), scleroderma, Raynaud's phenomenon and ischemia.
References Zamudio, T.P.: Arch. Cardiol. Mex., 77, 198 (2007); Lai, Y. et al.: Am. J. Resp. Crit. Care Med., 178, 188 (2008); Scorza, R. et al.: J. Rheutamol., 24, 1944 (1997); Melillo, E. et al.: Int. J. Microcircul. Clin. Exp., 15, 60 (1995);

Formula: C₂₂H₃₂O₄

Color and Shape: Neat

Molecular weight: 360.487

Ref: TR-I267315

16-(S)-Iloprost-d4

Controlled Product

CAS: 74843-14-4

Applications Labeled 16-(S)-Iloprost is the S-isomer of Iloprost (I267300), a synthetic analogue of Prostacyclin (PGI2) used to treat pulmonary arterial hypertension (PAH), scleroderma, Raynaud's phenomenon and ischemia.
References Zamudio, T.P.: Arch. Cardiol. Mex., 77, 198 (2007); Lai, Y. et al.: Am. J. Resp. Crit. Care Med., 178, 188 (2008); Scorza, R. et al.: J. Rheutamol., 24, 1944 (1997); Melillo, E. et al.: Int. J. Microcircul. Clin. Exp., 15, 60 (1995);

Formula: C₂₂D₄H₂₈O₄

Color and Shape: Neat

Molecular weight: 364.512

Ref: TR-I267317

16-(S)- Iloprost

CAS: 74843-14-4

Formula: C₂₂H₃₂O₄

Molecular weight: 360.5

Ref: ST-EA-CP-I58001

16(S)-Iloprost

CAS: 74843-14-4

Iloprost, a potent prostacyclin analog, binds to human IP & EP1 receptors with high affinity; inhibits platelet aggregation effectively.

Formula: C₂₂H₃₂O₄

Color and Shape: Solid

Molecular weight: 360.49

Ref: TM-T36212