CAS 74844-91-0

(2S,4R)-4-Hydroxypyrrolidine-1,2-dicarboxylic acid 1-tert-butyl ester 2-methyl ester

Description:

The chemical substance known as (2S,4R)-4-Hydroxypyrrolidine-1,2-dicarboxylic acid 1-tert-butyl ester 2-methyl ester, with the CAS number 74844-91-0, is a derivative of pyrrolidine, a five-membered nitrogen-containing heterocycle. This compound features multiple functional groups, including hydroxyl, carboxylic acid, and ester moieties, which contribute to its reactivity and potential applications in organic synthesis and medicinal chemistry. The presence of stereocenters in its structure indicates that it can exist in different stereoisomeric forms, which may influence its biological activity and interaction with other molecules. The tert-butyl and methyl ester groups enhance its lipophilicity, potentially affecting its solubility and permeability in biological systems. Such compounds are often investigated for their roles in drug development, particularly in the context of amino acid analogs or as intermediates in the synthesis of more complex molecules. Overall, the unique structural features of this compound make it a subject of interest in various chemical research fields.

Formula: C₁₁H₁₉NO₅

InChI: InChI=1S/C11H19NO5/c1-11(2,3)17-10(15)12-6-7(13)5-8(12)9(14)16-4/h7-8,13H,5-6H2,1-4H3/t7-,8+/m1/s1

InChI key: InChIKey=MZMNEDXVUJLQAF-SFYZADRCSA-N

SMILES: C(OC(C)(C)C)(=O)N1[C@H](C(OC)=O)C[C@@H](O)C1

Synonyms:

• (2S,4R)-1-Boc-4-Hydroxy-Proline Methylester
• (2S,4R)-1-tert-Butoxycarbonyl-2-(methoxycarbonyl)-4-hydroxypyrrolidine
• (2S,4R)-1-tert-Butoxycarbonyl-4-hydroxypyrrolidine-2-carboxylic acid methyl ester
• (2S,4R)-1-tert-butyl 2-methyl 4-hydroxypyrrolidine-1,2-dicarboxylate
• (2S,4R)-4-Hydroxypyrrolidine-1,2-dicarboxylic acid 1-tert-butyl ester 2-methyl ester
• (2S,4R)-Methyl 1-(tert-butyloxycarbonyl)-4-hydroxypyrrolidine-2-carboxylate
• 1,2-Pyrrolidinedicarboxylic acid, 4-hydroxy-, 1-(1,1-dimethylethyl) 2-methyl ester, (2S,4R)-
• 1,2-Pyrrolidinedicarboxylic acid, 4-hydroxy-, 1-(1,1-dimethylethyl) 2-methyl ester, (2S-trans)-
• 1-tert-Butyl 2-methyl (2S,4R)-4-hydroxy-1,2-pyrrolidinedicarboxylate
• 1-tert-Butyl 2-methyl 4(R)-hydroxypyrrolidine-1,2(S)-dicarboxylate
• 1-tert-butyl 2-methyl (2S,4R)-4-hydroxypyrrolidine-1,2-dicarboxylate
• BOC-L-Hydroxyproline methyl ester
• Boc-trans-4-hydroxy-L-proline methyl ester
• Methyl (2S,4R)-1-(tert-butoxycarbonyl)-4-hydroxypyrrolidine-2-carboxylate
• Methyl (2S,4R)-N-tert-Butoxycarbonyl-4-hydroxy-2-pyrrolidinecarboxylate
• Methyl (4R)-N-Boc-4-hydroxy-<span class="text-smallcaps">L</span>-prolinate
• Methyl N-tert-butoxycarbonyl-<span class="text-smallcaps">L</span>-hydroxyprolinate
• N-(tert-Butoxycarbonyl)-(2S,4R)-4-hydroxyproline methyl ester
• N-(tert-Butoxycarbonyl)-trans-4-hydroxy-L-proline Methyl Ester
• N-(tert-Butoxycarbonyl)-trans-hydroxy-L-proline methyl ester
• N-(tert-butoxycarbonyl)-cis-4-hydroxy-L-proline Methyl ester
• N-BOC-trans-4-hydroxy-L-proline methyl ester
• N-Boc-4-hydroxy-<span class="text-smallcaps">L</span>-proline methyl ester
• N-Boc-trans-4-hydroxy-L-prolinemethylester
• N-Boc-trans-4-hydroxyproline methyl ester
• N-tert-Butoxycarbonyl-<span class="text-smallcaps">L</span>-hydroxyproline methyl ester
• O1-tert-butyl O2-methyl (2S,4R)-4-hydroxypyrrolidine-1,2-dicarboxylate
• tert-Butyl (2S,4R)-2-(methoxycarbonyl)-4-hydroxypyrrolidine-1-carboxylate
• tert-Butyl methyl (2S,4R)-4-hydroxypyrrolidine-1,2-dicarboxylate
• N-Boc-4-hydroxy-L-proline methyl ester
• N-tert-Butoxycarbonyl-L-hydroxyproline methyl ester

N-(tert-Butoxycarbonyl)-trans-4-hydroxy-L-proline Methyl Ester

CAS: 74844-91-0

Formula: C₁₁H₁₉NO₅

Purity: >95.0%(GC)

Color and Shape: White to Almost white powder to crystal

Molecular weight: 245.28

Ref: 3B-B3843

N-Boc-trans-4-hydroxy-L-proline methyl ester, 97%

CAS: 74844-91-0

It is used in the synthesis of For-Met-Leu-Phe-OMe (fMLF-OMe) analogues based on Met residue replacement by 4-amino-proline scaffold. This Thermo Scientific Chemicals brand product was originally part of the Alfa Aesar product portfolio. Some documentation and label information may refer to the leg

Formula: C₁₁H₁₉NO₅

Purity: 97%

Color and Shape: White to yellow, Powder

Molecular weight: 245.28

Ref: 02-H59027

Boc-Hyp-OMe

CAS: 74844-91-0

Formula: C₁₁H₁₉NO₅

Purity: 97%

Color and Shape: Solid

Molecular weight: 245.2723

Ref: IN-DA003SU8

1-tert-Butyl 2-methyl (2S,4R)-4-hydroxypyrrolidine-1,2-dicarboxylate

CAS: 74844-91-0

1-tert-Butyl 2-methyl (2S,4R)-4-hydroxypyrrolidine-1,2-dicarboxylate

Formula: C₁₁H₁₉NO₅

Purity: 98%

Color and Shape: white solid

Molecular weight: 245.27225g/mol

Ref: 54-OR43520

N-Boc-trans-4-hydroxy-L-proline methyl ester

CAS: 74844-91-0

Formula: C₁₁H₁₉NO₅

Molecular weight: 245.28

Ref: 7W-GM9399

Boc-Hyp-OMe

CAS: 74844-91-0

M03218 - Boc-Hyp-OMe

Formula: C₁₁H₁₉NO₅

Purity: 97%

Color and Shape: Solid, Chunks or Crystalline Powder

Molecular weight: 245.275

Ref: 10-M03218

Boc-L-4-trans-hydroxyproline methyl ester

CAS: 74844-91-0

Boc-L-4-trans-hydroxyproline methyl ester is a triazolium compound that has been shown to have anticancer activity. It works by inhibiting the gyrase enzyme, which is responsible for maintaining the integrity of bacterial DNA. Boc-L-4-trans-hydroxyproline methyl ester is used in the treatment of various cancers, including lung cancer, breast cancer, and melanoma. Furthermore, it has been shown to inhibit viral replication and exhibits cytotoxic effects on cells. This drug can also be used as a probe for studying cellular morphology and protease activity.

Formula: C₁₁H₁₉NO₅

Purity: Min. 95%

Color and Shape: Powder

Molecular weight: 245.27 g/mol

Ref: 3D-FB47921

(2S,4R)-4-Hydroxypyrrolidine-1,2-dicarboxylic Acid 1-tert-Butyl Ester 2-Methyl Ester

Controlled Product

CAS: 74844-91-0

Formula: C₁₁H₁₉NO₅

Color and Shape: Neat

Molecular weight: 245.27

Ref: TR-H656560