CAS 749-49-5

Quinine lactate

Description:

Quinine lactate is a chemical compound derived from quinine, which is an alkaloid obtained from the bark of the cinchona tree. It is primarily known for its use as an antimalarial agent and has been utilized in various medicinal applications. Quinine lactate appears as a white to off-white crystalline powder and is soluble in water, which enhances its bioavailability for therapeutic use. The compound exhibits a bitter taste, characteristic of quinine derivatives, and is often used in formulations for treating nocturnal leg cramps and other conditions. Its pharmacological properties include antipyretic, analgesic, and anti-inflammatory effects. Quinine lactate is also recognized for its ability to inhibit certain types of parasites, making it valuable in the treatment of malaria. However, it is essential to use this compound under medical supervision due to potential side effects, including cinchonism, which can manifest as tinnitus, headache, and nausea. Overall, quinine lactate serves as an important compound in both pharmacology and medicinal chemistry.

Formula: C₂₀H₂₄N₂O₂·C₃H₆O₃

InChI: InChI=1S/C20H24N2O2.C3H6O3/c1-3-13-12-22-9-7-14(13)10-19(22)20(23)16-6-8-21-18-5-4-15(24-2)11-17(16)18;1-2(4)3(5)6/h3-6,8,11,13-14,19-20,23H,1,7,9-10,12H2,2H3;2,4H,1H3,(H,5,6)/t13-,14-,19-,20+;/m0./s1

InChI key: InChIKey=ZIDGEHZBXVXPFQ-DSXUQNDKSA-N

SMILES: [C@@H](O)(C=1C2=C(C=CC(OC)=C2)N=CC1)[C@]3([N@@]4C[C@H](C=C)[C@](C3)(CC4)[H])[H].C(C(O)=O)(C)O

Synonyms:

• Quinine, monolactate (salt)
• Quinine lactate
• Cinchonan-9-ol, 6′-methoxy-, (8α,9R)-, mono(2-hydroxypropanoate) (salt)
• Lactic acid, compd. with quinine (1:1)
• Propanoic acid, 2-hydroxy-, compd. with (8α,9R)-6′-methoxycinchonan-9-ol (1:1)