CAS 74970-31-3

Cephalosporin C sodium

Description:

Cephalosporin C sodium is a broad-spectrum antibiotic belonging to the cephalosporin class of β-lactam antibiotics. It is derived from the fungus Acremonium chrysogenum and is primarily used in the treatment of bacterial infections. The compound exhibits a β-lactam ring structure, which is crucial for its antibacterial activity, as it inhibits bacterial cell wall synthesis. Cephalosporin C sodium is typically administered in its sodium salt form to enhance solubility and stability. It is effective against a wide range of Gram-positive and Gram-negative bacteria, making it a valuable therapeutic agent in clinical settings. The substance is generally characterized by its white to off-white crystalline powder appearance and is soluble in water. Its pharmacological properties include a relatively low toxicity profile, although it may cause allergic reactions in some individuals, particularly those with a history of penicillin allergies. As with other antibiotics, appropriate susceptibility testing is recommended to ensure efficacy against specific bacterial strains.

Formula: C₁₆H₂₂N₃NaO₈S

InChI: InChI=1S/C16H21N3O8S.Na/c1-7(20)27-5-8-6-28-14-11(13(22)19(14)12(8)16(25)26)18-10(21)4-2-3-9(17)15(23)24;/h9,11,14H,2-6,17H2,1H3,(H,18,21)(H,23,24)(H,25,26);/t9-,11-,14-;/m1./s1

InChI key: InChIKey=FXNKJYIUBVTBDA-OOARYINLSA-N

SMILES: C(O)(=O)C=1N2[C@@]([C@H](NC(CCC[C@H](C(O)=O)N)=O)C2=O)(SCC1COC(C)=O)[H].[Na]

Synonyms:

• 5-Thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid, 3-[(acetyloxy)methyl]-7-[[(5R)-5-amino-5-carboxy-1-oxopentyl]amino]-8-oxo-, sodium salt, (6R,7R)-
• 5-Thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid, 3-[(acetyloxy)methyl]-7-[[(5R)-5-amino-5-carboxy-1-oxopentyl]amino]-8-oxo-, sodium salt (1:?), (6R,7R)-
• 5-Thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid, 3-[(acetyloxy)methyl]-7-[(5-amino-5-carboxy-1-oxopentyl)amino]-8-oxo-, sodium salt, [6R-[6α,7β(R*)]]-
• Cephalosporin C sodium