CAS 7499-07-2

4-Chloro-2-methylbenzoic acid

Description:

4-Chloro-2-methylbenzoic acid, with the CAS number 7499-07-2, is an aromatic carboxylic acid characterized by the presence of a chloro group and a methyl group on a benzoic acid framework. This compound features a chlorine atom at the para position and a methyl group at the ortho position relative to the carboxylic acid functional group. It typically appears as a white to off-white solid and is sparingly soluble in water, but more soluble in organic solvents such as ethanol and acetone. The presence of the chloro substituent can influence its reactivity and polarity, making it useful in various chemical syntheses and applications, including pharmaceuticals and agrochemicals. Additionally, 4-chloro-2-methylbenzoic acid can undergo typical reactions of carboxylic acids, such as esterification and acid-base reactions. Its unique structure allows it to participate in electrophilic aromatic substitution reactions, making it a versatile intermediate in organic synthesis. Safety precautions should be taken when handling this compound, as it may pose health risks if ingested or inhaled.

Formula: C₈H₇ClO₂

InChI: InChI=1/C8H7ClO2/c1-5-4-6(9)2-3-7(5)8(10)11/h2-4H,1H3,(H,10,11)

InChI key: InChIKey=XXFKOBGFMUIWDH-UHFFFAOYSA-N

SMILES: Cc1cc(ccc1C(=O)O)Cl

4-Chloro-2-methylbenzoic acid, 98%

CAS: 7499-07-2

This Thermo Scientific Chemicals brand product was originally part of the Alfa Aesar product portfolio. Some documentation and label information may refer to the legacy brand. The original Alfa Aesar product / item code or SKU reference has not changed as a part of the brand transition to Thermo Sci

Formula: C₈H₇ClO₂

Purity: 98%

Color and Shape: White, powder

Molecular weight: 170.59

Ref: 02-H27262

4-Chloro-2-methylbenzoic acid

CAS: 7499-07-2

Formula: C₈H₇ClO₂

Purity: 97%

Color and Shape: Solid

Molecular weight: 170.5930

Ref: IN-DA003L3T

4-Chloro-2-methylbenzoic acid

CAS: 7499-07-2

4-Chloro-2-methylbenzoic acid

Formula: C₈H₇ClO₂

Purity: 98%

Color and Shape: off white crystals / powder

Molecular weight: 170.59g/mol

Ref: 54-OR0251

4-Chloro-2-methylbenzoic Acid

CAS: 7499-07-2

Formula: C₈H₇ClO₂

Purity: >98.0%(GC)(T)

Color and Shape: White to Light yellow to Light orange powder to crystal

Molecular weight: 170.59

Ref: 3B-C2508

4-Chloro-2-methylbenzoic acid

CAS: 7499-07-2

Formula: C₈H₇ClO₂

Purity: 97%

Color and Shape: Solid

Molecular weight: 170.59

Ref: 10-F018393

4-Chloro-2-methylbenzoic acid

CAS: 7499-07-2

4-Chloro-2-methylbenzoic acid is a high quality chemical that is used as an intermediate in the preparation of other compounds. It belongs to the group of complex compounds and has CAS No. 7499-07-2. This reagent can be used to synthesize speciality chemicals, research chemicals, and versatile building blocks. 4-Chloro-2-methylbenzoic acid is also useful as a reaction component for the synthesis of fine chemicals, pharmaceuticals, and agrochemicals.

Formula: C₈H₇ClO₂

Purity: Min. 95%

Molecular weight: 170.59 g/mol

Ref: 3D-FC55109

4-Chloro-2-methylbenzoic Acid

Controlled Product

CAS: 7499-07-2

Applications 4-Chloro-2-methylbenzoic Acid is used as a reagent in organic synthesis including that of diarylamides which have a pyrimidinyl pyridine scaffold which show promising anti-proliferative effects on melanoma cancer cell lines. It is also used in the preparation of analogs of lenalidomide and pomalidomide for use as anti inflammatory and antitumor agents.
References Abdelazem, A., et al.: Bioorg. Med. Chem. Lett., 26, 1301 (2016); Ruchelman, A., et al.: Bioorg. Med. Chem. Lett., 23, 360 (2013);

Formula: C₈H₇ClO₂

Color and Shape: Neat

Molecular weight: 170.59

Ref: TR-C427685