CAS 75078-91-0

Temarotene

CAS: 75078-91-0

Temarotene

Purity: ≥95%

Molecular weight: 304.47g/mol

Ref: 54-BUP21556

Temarotene

CAS: 75078-91-0

Temarotene is an all-trans retinoic acid (ATRA) analog that binds to the IL-2 receptor with high affinity and specificity. It has been shown to inhibit the proliferation of HL-60 cells in vitro, which may be due to its ability to induce the release of colony-stimulating factor from these cells. Temarotene also enhances the uptake of ATRA by HL-60 cells and increases the expression of receptors for ATRA in humans. In vivo studies have shown that temarotene is a potent inducer of fatty acid synthesis in Sprague-Dawley rats. This agent has a long half-life and is rapidly absorbed when administered orally, with peak plasma concentrations occurring 2 hours after administration. The pharmacokinetic properties of this drug are similar to those of other synthetic retinoids, such as all-trans-retinoic acid.

Formula: C₂₃H₂₈

Purity: Min. 95%

Molecular weight: 304.5 g/mol

Ref: 3D-ADA07891

Temarotene

CAS: 75078-91-0

Temarotene (Ro 15-0778) is an orally active and potent small molecule compound that modulates human immune function in vitro.Temarotene may be used in the study

Formula: C₂₃H₂₈

Purity: 97.54%

Color and Shape: Solid

Molecular weight: 304.47

Ref: TM-T17034