CAS 751-84-8

benethamine penicillin

Description:

Benethamine penicillin, with the CAS number 751-84-8, is a type of penicillin antibiotic that is primarily used for the treatment of bacterial infections. It is a combination of penicillin and benethamine, which enhances its absorption and prolongs its action in the body. This compound is characterized by its ability to inhibit bacterial cell wall synthesis, making it effective against a variety of gram-positive bacteria. Benethamine penicillin is typically administered via intramuscular injection due to its poor oral bioavailability. The substance is known for its relatively long half-life, allowing for less frequent dosing compared to other penicillins. Commonly used in the treatment of syphilis and other infections, it is important to note that individuals with penicillin allergies should avoid this medication. As with other antibiotics, the emergence of resistance is a concern, necessitating careful use and adherence to prescribed regimens. Overall, benethamine penicillin remains a valuable tool in the field of infectious disease treatment.

Formula: C₃₁H₃₅N₃O₄S

InChI: InChI=1/C16H18N2O4S.C15H17N/c1-16(2)12(15(21)22)18-13(20)11(14(18)23-16)17-10(19)8-9-6-4-3-5-7-9;1-3-7-14(8-4-1)11-12-16-13-15-9-5-2-6-10-15/h3-7,11-12,14H,8H2,1-2H3,(H,17,19)(H,21,22);1-10,16H,11-13H2/t11-,12+,14-;/m1./s1

InChI key: InChIKey=JAQPGQYDZJZOIN-LQDWTQKMSA-N

SMILES: C(O)(=O)[C@@H]1N2[C@@]([C@H](NC(CC3=CC=CC=C3)=O)C2=O)(SC1(C)C)[H].C(CNCC1=CC=CC=C1)C2=CC=CC=C2

Synonyms:

• (2S,5R,6R)-3,3-dimethyl-7-oxo-6-[(phenylacetyl)amino]-4-thia-1-azabicyclo[3.2.0]heptane-2-carboxylic acid - N-benzyl-2-phenylethanamine (1:1)
• 3,3-Dimethyl-7-Oxo-6-[(Phenylacetyl)Amino]-4-Thia-1-Azabicyclo[3.2.0]Heptane-2-Carboxylic Acid
• 4-Thia-1-azabicyclo[3.2.0]heptane-2-carboxylic acid, 3,3-dimethyl-7-oxo-6-[(2-phenylacetyl)amino]- (2S,5R,6R)-, compd. with N-(phenylmethyl)benzeneethanamine (1:1)
• 4-Thia-1-azabicyclo[3.2.0]heptane-2-carboxylic acid, 3,3-dimethyl-7-oxo-6-[(phenylacetyl)amino]- (2S,5R,6R)-, compd. with N-(phenylmethyl)benzeneethanamine (1:1)
• 4-Thia-1-azabicyclo[3.2.0]heptane-2-carboxylic acid, 3,3-dimethyl-7-oxo-6-[(phenylacetyl)amino]- [2S-(2α,5α,6β)]-, compd. with N-(phenylmethyl)benzeneethanamine (1:1)
• Benapen
• Benetacil
• Benethamine penicillin G
• Benetolin
• Benzeneethanamine, N-(phenylmethyl)-, (2S,5R,6R)-3,3-dimethyl-7-oxo-6-[(phenylacetyl)amino]-4-thia-1-azabicyclo[3.2.0]heptane-2-carboxylate
• Benzeneethanamine, N-(phenylmethyl)-, [2S-(2α,5α,6β)]-3,3-dimethyl-7-oxo-6-[(phenylacetyl)amino]-4-thia-1-azabicyclo[3.2.0]heptane-2-carboxylate
• Benzylpenicillin N-benzyl-2-phenylethylamine salt
• Benzylpenicillinic acid N-benzyl-β-phenylethylamine salt
• Betapen
• N-Benzyl-2-phenylethylamine salt of benzylpenicillin
• N-Benzylphenethylamine benzylpenicillin salt
• N-benzylphenethylammonium 6-phenylacetamidopenicillanate
• Penicillin G benethamine
• Penicillin G, N-benzylphenethylamine salt
• Phenethylamine, N-benzyl-, 3,3-dimethyl-7-oxo-6-(2-phenylacetamido)-4-thia-1-azabicyclo[3.2.0]heptane-2-carboxylate

Benethamine penicillin

Controlled Product

CAS: 751-84-8

Benethamine penicillin is a beta-lactam antibiotic, which is a semi-synthetic derivative of penicillin. It is sourced from the modification of naturally occurring penicillin compounds, typically produced through the fermentation of Penicillium mold cultures. Benethamine penicillin operates by inhibiting bacterial cell wall synthesis. It targets the penicillin-binding proteins within bacterial cell membranes, disrupting peptidoglycan cross-linking, which is essential for cell wall structural integrity. This leads to cell lysis and death in susceptible bacteria.

Formula: C₁₆H₁₈N₂O₄S·C₁₅H₁₇N

Purity: Min. 95%

Molecular weight: 545.69 g/mol

Ref: 3D-FB171055

Benethamine penicillin

CAS: 751-84-8

Benethamine penicillin

Color and Shape: Off White Solid

Ref: 47-432