CAS 751-94-0

Sodium fusidate

Description:

Sodium fusidate is a sodium salt of fusidic acid, which is an antibiotic derived from the fungus Fusidium coccineum. It is primarily used for its antibacterial properties, particularly against Gram-positive bacteria, including Staphylococcus aureus. Sodium fusidate is characterized by its ability to inhibit bacterial protein synthesis by interfering with the function of the ribosome, making it effective in treating skin infections, osteomyelitis, and other conditions caused by susceptible bacteria. The compound is typically administered in topical formulations or orally, depending on the infection being treated. It is known for its relatively low toxicity and good tolerability in patients. In terms of physical properties, sodium fusidate is a white to off-white powder that is soluble in water, which facilitates its use in various pharmaceutical preparations. However, like all antibiotics, its use should be guided by susceptibility testing to prevent the development of resistance.

Formula: C₃₁H₄₇NaO₆

InChI: InChI=1/C31H48O6.Na/c1-17(2)9-8-10-20(28(35)36)26-22-15-24(34)27-29(5)13-12-23(33)18(3)21(29)11-14-30(27,6)31(22,7)16-25(26)37-19(4)32;/h9,18,21-25,27,33-34H,8,10-16H2,1-7H3,(H,35,36);/q;+1/p-1/b26-20+;/t18-,21-,22-,23+,24+,25-,27-,29-,30-,31-;/m0./s1

InChI key: InChIKey=ZUMDNSFJFSGPGY-JCJNLNMISA-N

SMILES: C[C@@]12[C@]3(C)[C@](/C(=C(\CCC=C(C)C)/C(O)=O)/[C@@H](OC(C)=O)C3)(C[C@@H](O)[C@]1([C@]4(C)[C@@](CC2)([C@H](C)[C@H](O)CC4)[H])[H])[H].[Na]

Synonyms:

• (3Alpha,4Alpha,8Alpha,9Beta,11Alpha,13Alpha,14Beta,16Beta,17Z)-16-(Acetyloxy)-3,11-Dihydroxy-29-Nordammara-17(20),24-Dien-21-Oic Acid
• 16-(Acetyloxy)-3,11-Dihydroxy-29-Nordammara-17(20),24-Dien-21-Oic Acid Sodium Salt
• 29-Nor-8α,9β,13α,14β-dammara-17(20),24-dien-21-oic acid, 3α,11α,16β-trihydroxy-, 16-acetate, monosodium salt, (Z)-
• 29-Nordammara-17(20),24-dien-21-oic acid, 16-(acetyloxy)-3,11-dihydroxy-, monosodium salt, (3α,4α,8α,9β,11α,13α,14β,16β,17Z)-
• 29-Nordammara-17(20),24-dien-21-oic acid, 16-(acetyloxy)-3,11-dihydroxy-, sodium salt (1:1), (3α,4α,8α,9β,11α,13α,14β,16β,17Z)-
• Fucidin
• Fucidina
• Fucidine
• Fusidate sodium
• Fusidatesodium
• Fusidic
• Fusidic Acid Sodium
• Fusidic Acid Sodium (Sodium Fusidate)
• Fusidic Acid Sodium Salt 98%
• Fusidic acid sodium salt
• Fusidin
• Fusin
• Intertullefucidin
• Sodium Fusidate Bp/Ip
• Sodium fucidate
• Sodium fusidin
• Sodiumfusidin
• Sq 16360
• Sq16360
• ZN 6-Na
• sodium (2E)-2-[(3alpha,4alpha,5alpha,8alpha,9beta,11alpha,13alpha,14beta,16beta,17E)-16-(acetyloxy)-3,11-dihydroxy-4,8,10,14-tetramethylgonan-17-ylidene]-6-methylhept-5-enoate
• sodium (2Z)-2-[(3alpha,4alpha,5alpha,8alpha,9beta,11alpha,13alpha,14beta,16beta,17Z)-16-(acetyloxy)-3,11-dihydroxy-4,8,10,14-tetramethylgonan-17-ylidene]-6-methylhept-5-enoate
• zn6
• SODIUM FUSIDATE
• FUSIDIC ACID
• 16-(acetyloxy)-3,11-dihydroxy-29-nordammara-17(20),24-dien-21-oic acid
• fusidine

Fusidic acid sodium

CAS: 751-94-0

An antitubercular antibiotic which inhibits cell wall formation in Mycobacterium species

Formula: C₃₁H₄₇NaO₆

Molecular weight: 538.69

Ref: 02-J66703

SODIUM FUSIDATE CRS

CAS: 751-94-0

SODIUM FUSIDATE CRS

Formula: C₃₁H₄₇NaO₆

Color and Shape: Crystalline Powder. White.

Molecular weight: 538.691

Ref: 41-Y0001410

Fusidic acid sodium salt

CAS: 751-94-0

Fusidic acid sodium salt (SQ-16360) is a sodium salt form of fusidic acid, a bacteriostatic antibiotic derived from the fungus Fusidium coccineum.

Formula: C₃₁H₄₇NaO₆

Purity: 99.81% - 99.84%

Color and Shape: While Crystalline Power

Molecular weight: 538.69

Ref: TM-T1289

Fusidic acid sodium salt

CAS: 751-94-0

Formula: C₃₁H₄₇NaO₆

Purity: 98%

Color and Shape: Solid

Molecular weight: 538.6910

Ref: IN-DA005639

Fusidic acid sodium salt

CAS: 751-94-0

Fusidic acid sodium salt

Color and Shape: Solid

Molecular weight: 538.69g/mol

Ref: 54-BIF6401

Fusidic acid sodium salt

CAS: 751-94-0

Fusidic acid sodium salt

Purity: ≥98%

Molecular weight: 538.69g/mol

Ref: 54-BUP16884

Fusidic acid sodium salt

CAS: 751-94-0

Formula: C₃₁H₄₇O₆Na

Purity: 97.5 - 101.5 % (anhydrous basis)

Color and Shape: White or almost white crystalline powder

Molecular weight: 538.7

Ref: 7W-GA1411

Fusidic acid sodium salt, EP grade

CAS: 751-94-0

Formula: C₃₁H₄₇O₆Na

Purity: (Titration) 97.5 - 101.0 % (anhydrous substance)

Color and Shape: White or almost white crystalline powder

Molecular weight: 538.7

Ref: 7W-GA8310

Fusidate Sodium

CAS: 751-94-0

Formula: C₃₁H₄₇NaO₆

Purity: >95.0%(T)(HPLC)

Color and Shape: White to Light yellow powder to crystal

Molecular weight: 538.70

Ref: 3B-O0613

Sodium Fusidate

Controlled Product

CAS: 751-94-0

Formula: C₃₁H₄₇O₆·Na

Color and Shape: Neat

Molecular weight: 538.69

Ref: 86-MM0831.00

Fusidic Acid Sodium Salt

Controlled Product

CAS: 751-94-0

Applications Fusidic Acid Sodium Salt is a bacteriostatic antibiotic. Fusidic Acid suppresses nitric oxide lysis of pancreatic islet cells. Inhibits protein synthesis in prokaryotes by inhibiting the ribosome-dependent activity of G factor and translocation of peptidyl-tRNA.
References Collignon, P., et al.: Int. J. Antimicrob. Agents, 12, S45 (1999); Di Marco, R., et al.: J. Autoimmun., 13, 187 (1999); Price, C.T., et al.: J. Antimicrob., Chemother., 44, 57 (1999)

Formula: C₃₁H₄₇O₆·Na

Color and Shape: Neat

Molecular weight: 538.69

Ref: TR-F865505

Fusidic acid sodium

CAS: 751-94-0

Inhibitor of protein synthesis; steroid antibiotic

Formula: C₃₁H₄₈O₆•Na

Purity: Min. 95%

Color and Shape: Powder

Molecular weight: 539.7 g/mol

Ref: 3D-FF153145

Sodium Fucidate (Na-FC), 97.5%

CAS: 751-94-0

Formula: C₃₁H₄₇O₆Na

Purity: min. 97.5%

Color and Shape: White to off White, Crystalline powder, Clear

Molecular weight: 538.70

Ref: SR-36511