CAS 75202-36-7

Timolol EP Impurity G

Description:

Timolol EP Impurity G, with the CAS number 75202-36-7, is a chemical compound that is recognized as an impurity associated with the pharmaceutical agent timolol, which is primarily used in the treatment of glaucoma and hypertension. This impurity is characterized by its specific molecular structure, which may differ slightly from the parent compound, timolol, affecting its pharmacological properties. Typically, impurities like Timolol EP Impurity G are monitored for their potential impact on the efficacy and safety of the drug formulation. The compound may exhibit distinct physical and chemical properties, such as solubility, stability, and reactivity, which are crucial for quality control in pharmaceutical manufacturing. Regulatory guidelines often require the identification and quantification of such impurities to ensure that they remain within acceptable limits to maintain drug safety and effectiveness. Understanding the characteristics of impurities like Timolol EP Impurity G is essential for pharmaceutical development and compliance with health regulations.

Formula: C₆H₉N₃O₃S

Synonyms:

• Timolol Impurity 7（Timolol EP Impurity G）
• 3-Hydroxy-4-morpholino-1,2,5-thiadi
• 4-(Morpholin-4-yl)-1,2,5-thiadiazol-3(2H)-one 1-oxide
• Timolol Maleate EP Impurity G
• 4-morpholino-1,2,5-thiadiazol-3(2H)-one 1-oxide
• 1,2,5-Thiadiazol-3(2H)-one, 4-(4-morpholinyl)-, 1-oxide
• Timolol EP Impurity G
• 4-(4-Morpholinyl)-1,2,5-thiadiazol-3(2H)-one 1-Oxide
• 4-morpholin-4-yl-1-oxo-1,2,5-thiadiazol-3-one

Hydroxythiadiazol Sulfoxide Derivative (4-morpholino-1,2,5-thiadiazol-3(2H)-one 1-oxide)

CAS: 75202-36-7

Nucleic acids and their salts, whether or not chemically defined; other heterocyclic compounds, nesoi

Formula: C₆H₉N₃O₃S

Color and Shape: White Off-White Solid

Molecular weight: 203.03646

Ref: 45-1A00040

Timolol EP Impurity G

CAS: 75202-36-7

Formula: C₆H₉N₃O₃S

Color and Shape: White To Off-White Solid

Molecular weight: 203.22

Ref: 4Z-T-68014

3-Hydroxy-4-morpholino-1,2,5-thiadiazole 1-Oxide

Controlled Product

CAS: 75202-36-7

Formula: C₆H₉N₃O₃S

Color and Shape: Neat

Molecular weight: 203.22

Ref: 86-MM0440.05

4-​(4-Morpholinyl)​-1,​2,​5-​thiadiazol-​3(2H)​-​one 1-Oxide

Controlled Product

CAS: 75202-36-7

Impurity Timolol EP Impurity G; Timolol BP Impurity G
Stability Moisture Sensitive
Applications 4-​(4-Morpholinyl)​-1,​2,​5-​thiadiazol-​3(2H)​-​one 1-Oxide (Timolol EP Impurity G; Timolol BP Impurity G) is an impurity of Timolol (T4437005), an antihypertensive, an adrenergic blocking agent (1); antiarrhythmic (class II); antianginal; antiglaucoma (2) and antihypertensive (3) agent.
References 1. Wasson, B. et al.: J. Med. Chem. 1972 Jun;15(6):651-5.2. Heel, R. et al.: Drugs. 1979 Jan;17(1):38-55.3. Rofman, et al.: Hypertension. 1980 Sep-Oct;2(5):643-8.

Formula: C₆H₉N₃O₃S

Color and Shape: White

Molecular weight: 203.22

Ref: TR-M725175