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CAS 75217-63-9

:

Glucagon (swine),27-[4-(methylsulfinyl)-L-2-aminobutanoic acid]- (9CI)

Description:
Glucagon is a peptide hormone primarily produced by the alpha cells of the pancreas, playing a crucial role in glucose metabolism. The specific variant "Glucagon (swine), 27-[4-(methylsulfinyl)-L-2-aminobutanoic acid]- (9CI)" refers to a modified form of glucagon derived from swine, which includes a unique amino acid substitution that enhances its stability and activity. This modification can influence its pharmacokinetics and pharmacodynamics, making it useful in therapeutic applications, particularly in managing hypoglycemia and as a counter-regulatory hormone to insulin. The CAS number 75217-63-9 identifies this specific glucagon variant in chemical databases, facilitating research and regulatory processes. Glucagon acts by stimulating glycogenolysis and gluconeogenesis in the liver, leading to increased blood glucose levels. It is typically administered via injection and is essential in emergency situations for individuals with diabetes experiencing severe hypoglycemia. Overall, glucagon's characteristics, including its structure, function, and therapeutic applications, underscore its importance in endocrinology and metabolic regulation.
Formula:C153H225N43O50S
Synonyms:
  • Glucagon(pig), 27-[4-(methylsulfinyl)-L-2-aminobutanoic acid]-
  • (Met(O)27)-Glucagon (1-29) (Human, Bovine, Porcine)
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