CAS 75225-51-3

Lovastatin acid

Description:

Lovastatin acid, with the CAS number 75225-51-3, is a naturally occurring compound that is a derivative of lovastatin, a well-known cholesterol-lowering medication. It is classified as a statin, which functions by inhibiting the enzyme HMG-CoA reductase, a key player in the biosynthesis of cholesterol in the liver. Lovastatin acid is characterized by its molecular structure, which includes a lactone ring that is hydrolyzed to form the active acid form. This compound exhibits lipid-lowering properties and is primarily used in the management of hyperlipidemia and cardiovascular diseases. In addition to its pharmacological effects, lovastatin acid has been studied for its potential anti-inflammatory and antioxidant properties. It is typically administered in oral form and is well-absorbed in the gastrointestinal tract. However, like other statins, it may have side effects, including muscle pain and liver enzyme alterations, necessitating monitoring during treatment. Overall, lovastatin acid plays a significant role in modern medicine for managing cholesterol levels and reducing the risk of heart disease.

Formula: C₂₄H₃₈O₆

InChI: InChI=1S/C24H38O6/c1-5-15(3)24(29)30-21-11-14(2)10-17-7-6-16(4)20(23(17)21)9-8-18(25)12-19(26)13-22(27)28/h6-7,10,14-16,18-21,23,25-26H,5,8-9,11-13H2,1-4H3,(H,27,28)/t14-,15-,16-,18+,19+,20-,21-,23-/m0/s1

InChI key: InChIKey=QLJODMDSTUBWDW-BXMDZJJMSA-N

SMILES: C(C[C@H](C[C@H](CC(O)=O)O)O)[C@@H]1[C@]2([C@@H](OC([C@H](CC)C)=O)C[C@@H](C)C=C2C=C[C@@H]1C)[H]

Synonyms:

• 1-Naphthaleneheptanoic acid, 1,2,6,7,8,8a-hexahydro-β,δ-dihydroxy-2,6-dimethyl-8-[(2S)-2-methyl-1-oxobutoxy]-, (βR,δR,1S,2S,6R,8S,8aR)-
• Mevinolinic acid
• MSD 803 free acid
• 1-Naphthaleneheptanoic acid, 1,2,6,7,8,8a-hexahydro-β,δ-dihydroxy-2,6-dimethyl-8-(2-methyl-1-oxobutoxy)-, [1S-[1α(βS*,δS*),2α,6β,8β(R*),8aα]]-
• (βR,δR,1S,2S,6R,8S,8aR)-1,2,6,7,8,8a-Hexahydro-β,δ-dihydroxy-2,6-dimethyl-8-[(2S)-2-methyl-1-oxobutoxy]-1-naphthaleneheptanoic acid

Mevinolinic acid

CAS: 75225-51-3

Mevinolinic acid is an active metabolite of Lovastatin. Lovastatin is an HMG-CoA reductase inhibitor.

Formula: C₂₄H₃₈O₆

Purity: 98%

Color and Shape: Solid

Molecular weight: 422.562

Ref: TM-T24461