CAS 752253-39-7

4-(2-Chloro-4-methoxy-5-methylphenyl)-N-[(1S)-2-cyclopropyl-1-(3-fluoro-4-methylphenyl)ethyl]-5-methyl-N-2-propyn-1-yl-2-thiazolamine

Description:

The chemical substance known as "4-(2-Chloro-4-methoxy-5-methylphenyl)-N-[(1S)-2-cyclopropyl-1-(3-fluoro-4-methylphenyl)ethyl]-5-methyl-N-2-propyn-1-yl-2-thiazolamine," with the CAS number 752253-39-7, is a complex organic compound characterized by its multi-functional structure. It features a thiazole ring, which is a five-membered heterocyclic compound containing sulfur and nitrogen, contributing to its biological activity. The presence of various substituents, including a chloro group, methoxy group, and multiple methyl groups, suggests potential lipophilicity and the ability to interact with biological targets. The cyclopropyl and fluoro groups may enhance its pharmacological properties, possibly affecting its binding affinity and selectivity. This compound is likely to be investigated for its therapeutic potential, particularly in fields such as medicinal chemistry or drug development, due to its intricate structure that may influence its reactivity and biological interactions. As with many synthetic organic compounds, its stability, solubility, and reactivity would be critical factors in determining its practical applications.

Formula: C₂₇H₂₈ClFN₂OS

InChI: InChI=1S/C27H28ClFN2OS/c1-6-11-31(24(13-19-8-9-19)20-10-7-16(2)23(29)14-20)27-30-26(18(4)33-27)21-12-17(3)25(32-5)15-22(21)28/h1,7,10,12,14-15,19,24H,8-9,11,13H2,2-5H3/t24-/m0/s1

InChI key: InChIKey=IEAKXXNRGSLYTQ-DEOSSOPVSA-N

SMILES: [C@H](N(CC#C)C1=NC(=C(C)S1)C2=C(Cl)C=C(OC)C(C)=C2)(CC3CC3)C4=CC(F)=C(C)C=C4

Synonyms:

• SSR 125543
• Crinecerfont
• 2-Thiazolamine, 4-(2-chloro-4-methoxy-5-methylphenyl)-N-[(1S)-2-cyclopropyl-1-(3-fluoro-4-methylphenyl)ethyl]-5-methyl-N-2-propynyl-
• 4-(2-Chloro-4-methoxy-5-methylphenyl)-N-[(1S)-2-cyclopropyl-1-(3-fluoro-4-methylphenyl)ethyl]-5-methyl-N-2-propyn-1-yl-2-thiazolamine
• 2-Thiazolamine, 4-(2-chloro-4-methoxy-5-methylphenyl)-N-[(1S)-2-cyclopropyl-1-(3-fluoro-4-methylphenyl)ethyl]-5-methyl-N-2-propyn-1-yl-

Crinecerfont

CAS: 752253-39-7

Crinecerfont

Purity: ≥95%

Molecular weight: 483.04g/mol

Ref: 54-BUP08141

Crinecerfont

CAS: 752253-39-7

Formula: C₂₇H₂₈ClFN₂OS

Molecular weight: 482.16

Ref: 4Z-C-482001

Crinecerfont

CAS: 752253-39-7

Crinecerfont (SSR-125543) is a CRF1 antagonist, useful in congenital adrenal hyperplasia research.

Formula: C₂₇H₂₈ClFN₂OS

Purity: 97.79% - 98.55%

Color and Shape: Solid

Molecular weight: 483.04

Ref: TM-T31095