CAS: 752253-39-7 - 4-(2-Chloro-4-methoxy-5-methylphenyl)-N-[(1S)-2-cyclopropyl-1-(3-fluoro-4-methylphenyl)ethyl]-5-methyl-N-2-propyn-1-yl-2-thiazolamine

Formula: C₂₇H₂₈ClFN₂OS

InChI: InChI=1S/C27H28ClFN2OS/c1-6-11-31(24(13-19-8-9-19)20-10-7-16(2)23(29)14-20)27-30-26(18(4)33-27)21-12-17(3)25(32-5)15-22(21)28/h1,7,10,12,14-15,19,24H,8-9,11,13H2,2-5H3/t24-/m0/s1

InChI key: InChIKey=IEAKXXNRGSLYTQ-DEOSSOPVSA-N

SMILES: FC1=CC(=CC=C1C)C(N(C2=NC(C=3C=C(C(OC)=CC3Cl)C)=C(S2)C)CC#C)CC4CC4

Synonyms:

• SSR 125543
• Crinecerfont
• 2-Thiazolamine, 4-(2-chloro-4-methoxy-5-methylphenyl)-N-[(1S)-2-cyclopropyl-1-(3-fluoro-4-methylphenyl)ethyl]-5-methyl-N-2-propynyl-
• 4-(2-Chloro-4-methoxy-5-methylphenyl)-N-[(1S)-2-cyclopropyl-1-(3-fluoro-4-methylphenyl)ethyl]-5-methyl-N-2-propyn-1-yl-2-thiazolamine
• 2-Thiazolamine, 4-(2-chloro-4-methoxy-5-methylphenyl)-N-[(1S)-2-cyclopropyl-1-(3-fluoro-4-methylphenyl)ethyl]-5-methyl-N-2-propyn-1-yl-

Crinecerfont

CAS: 752253-39-7

Crinecerfont (SSR-125543) is a CRF1 antagonist, useful in congenital adrenal hyperplasia research.

• Formula: C₂₇H₂₈ClFN₂OS
• Purity: 98.01% - 99.10%
• Color and Shape: Solid
• Molecular weight: 483.04