CAS 75272-39-8

Nemonapride

Description:

Nemonapride is a chemical compound classified as an atypical antipsychotic and is primarily used in the treatment of various psychiatric disorders, particularly in managing symptoms of schizophrenia and other mood disorders. It acts as a selective dopamine D2 receptor antagonist, which helps to modulate neurotransmitter activity in the brain, thereby alleviating symptoms associated with these conditions. Nemonapride is known for its relatively favorable side effect profile compared to traditional antipsychotics, making it a preferred choice in certain clinical scenarios. The compound has a specific molecular structure characterized by its unique functional groups, which contribute to its pharmacological properties. Additionally, it exhibits moderate solubility in water and is typically administered in oral form. As with any medication, the use of nemonapride should be guided by a healthcare professional, considering potential interactions and contraindications. Overall, its therapeutic efficacy and safety profile make it a significant agent in psychiatric pharmacotherapy.

Formula: C₂₁H₂₆ClN₃O₂

InChI: InChI=1/C21H26ClN3O2/c1-14-18(9-10-25(14)13-15-7-5-4-6-8-15)24-21(26)16-11-17(22)19(23-2)12-20(16)27-3/h4-8,11-12,14,18,23H,9-10,13H2,1-3H3,(H,24,26)/t14-,18-/s2

InChI key: InChIKey=KRVOJOCLBAAKSJ-SHTGXJIWNA-N

SMILES: C(N[C@H]1[C@@H](C)N(CC2=CC=CC=C2)CC1)(=O)C3=C(OC)C=C(NC)C(Cl)=C3

Synonyms:

• (+-)-cis-N-(1-Benzyl-2-methylpyrrolidin-3-yl)-5-chloro-2-methoxy-4-methylaminobenzamide
• Benzamide, 5-chloro-2-methoxy-4-(methylamino)-N-(2-methyl-1-(phenylmethyl)-3-pyrrolidinyl)-, cis-(+-)-
• Benzamide, 5-chloro-2-methoxy-4-(methylamino)-N-[(2R,3R)-2-methyl-1-(phenylmethyl)-3-pyrrolidinyl]-, rel-
• Benzamide, 5-chloro-2-methoxy-4-(methylamino)-N-[2-methyl-1-(phenylmethyl)-3-pyrrolidinyl]-
• Emilace
• Emonapride
• N-(2RS,3RS)-(1-Benzyl-2-methyl-3-pyrrolidinyl)-5-chloro-2-methoxy-4-methylaminobenzamide
• Nemonapride
• Ym 09151
• Ym 09151-2
• rel-5-Chloro-2-methoxy-4-(methylamino)-N-[(2R,3R)-2-methyl-1-(phenylmethyl)-3-pyrrolidinyl]benzamide

Nemonapride

CAS: 75272-39-8

Formula: C₂₁H₂₆ClN₃O₂

Molecular weight: 387.90

Ref: 7W-GP3800

Nemonapride

CAS: 75272-39-8

Formula: C₂₁H₂₆ClN₃O₂

Molecular weight: 387.91

Ref: 4Z-N-175001

Nemonapride

Controlled Product

CAS: 75272-39-8

Applications Nemonapride is a selective dopamine D2 receptor antagonist. Nemonapride is used as an antipsychotic.
References Yamamoto, M., et al.: Neuropharmacology, 21, 945 (1982), Grewe, C.W., et al.: Eur. J. Pharmacol., 81, 149 (1982), Satoh, K., et al.: Int. Clin. Psychopharmacol., 11, 279 (1996)

Formula: C₂₁H₂₆ClN₃O₂

Color and Shape: Off-White

Molecular weight: 387.9

Ref: TR-N389825

Nemonapride

CAS: 75272-39-8

Dopamine receptor antagonist; antipsychotic

Formula: C₂₁H₂₆ClN₃O₂

Purity: Min. 95%

Molecular weight: 387.9 g/mol

Ref: 3D-FN26180

Nemonapride

CAS: 75272-39-8

Nemonapride is a dopamine D2-like receptor antagonist.

Formula: C₂₁H₂₆ClN₃O₂

Purity: 98%

Color and Shape: Solid

Molecular weight: 387.9

Ref: TM-T23063