CAS 75345-27-6

Polyquaternium 1

Description:

Polyquaternium-1 is a synthetic polymer that belongs to the class of quaternary ammonium compounds. It is primarily used in personal care products, particularly in hair conditioners, shampoos, and skin care formulations, due to its conditioning and film-forming properties. This polymer is known for its ability to improve the texture and manageability of hair, providing a smooth and soft feel. Polyquaternium-1 is water-soluble and exhibits good compatibility with various surfactants, making it an effective ingredient in formulations. Additionally, it has antimicrobial properties, which can enhance the preservation of cosmetic products. The polymer is generally considered safe for use in cosmetics and personal care items, with low irritation potential for skin and eyes. Its cationic nature allows it to adhere to negatively charged surfaces, such as hair and skin, providing long-lasting conditioning effects. Overall, Polyquaternium-1 is valued for its multifunctional benefits in enhancing the performance and sensory attributes of cosmetic formulations.

Formula: (C₆H₁₂N)nC₁₆H₃₆N₂O₆·3Cl

InChI: InChI=1S/C22H48N3O6/c1-23(2,7-3-5-9-24(11-17-26,12-18-27)13-19-28)8-4-6-10-25(14-20-29,15-21-30)16-22-31/h3-6,26-31H,7-22H2,1-2H3/q+3

InChI key: InChIKey=YOANRIBNDKBHCR-UHFFFAOYSA-N

SMILES: [N+](CC=CC[N+](CC=CC[N+](CCO)(CCO)CCO)(C)C)(CCO)(CCO)CCO.[Cl-]

Synonyms:

• (2E)-N,N,N-tris(2-hydroxyethyl)-N',N'-dimethyl-N'-{(2E)-4-[tris(2-hydroxyethyl)ammonio]but-2-en-1-yl}but-2-ene-1,4-diaminium trichloride
• Onamer M
• Onyxsperse 12S
• Pegaldesleukin
• Poly[(dimethyliminio)-2-butene-1,4-diyl chloride (1:1)], α-[4-[tris(2-hydroxyethyl)ammonio]-2-buten-1-yl]-ω-[tris(2-hydroxyethyl)ammonio]-, chloride (1:2)
• Poly[(dimethyliminio)-2-butene-1,4-diyl chloride], α-[4-[tris(2-hydroxyethyl)ammonio]-2-butenyl]-ω-[tris(2-hydroxyethyl)ammonio]-, dichloride
• Polyquad
• Polyquat 1
• Polyquaternium-1

Poly[(dimethyliminio)-2-butene-1,4-diyl chloride],a-[4-[tris(2-hydroxyethyl)ammonio]-2-butenyl]-w-[tris(2-hydroxyethyl)ammonio]-, dichloride

CAS: 75345-27-6

Formula: C₂₂H₄₈Cl₃N₃O₆

Purity: 95%

Color and Shape: Solid

Molecular weight: 556.9920

Ref: IN-DA00G3B1

Polyquaternium-1

CAS: 75345-27-6

Polyquaternium-1

Purity: ≥95%

Molecular weight: 556.99g/mol

Ref: 54-BUP06570

Polyquaternium 1

Controlled Product

CAS: 75345-27-6

Applications Polyquaternium 1 is an antimicrobial preservative used for rabbit ocular surface study on polyquad-preserved travoprost/timolol, benzalkonium chloride-preserved travoprost/timolol, and latanoprost/timolol in fixed combinations.
References Pisella, P., et al.: Br. J. Ophthalmol., 86, 418 (2002), Robin, A., et al.: Am. J. Ophthalmol., 144, 533 (2007), Schmier, J., et al.: Curr. Med. Res. Opin., 23, 2867 (2007),

Formula: (C₆H₁₂ClN)n·C₁₆H₃₆Cl₂N₂O₆

Color and Shape: Neat

Molecular weight: 556.99

Ref: TR-P688100

Polyquaternium 1

CAS: 75345-27-6

Polyquaternium 1 is a polymer that is used in the formulation of topical antimicrobial agents. It has been shown to have a toxicity profile that is similar to other polymers. Polyquaternium 1 has been shown to be active against a wide range of bacteria, including methicillin-resistant Staphylococcus aureus, and also exhibits activity against fungi. The mechanism of action for Polyquaternium 1 appears to be due to its ability to bind to the bacterial cell wall and prevent the attachment and growth of microorganisms on the surface. The acyl chain length may affect the efficacy of this polymer. Polyquaternium 1 is synthesized by free radical polymerization methods such as atom transfer radical polymerization (ATRP), which can produce linear chains with uniform acyl chain lengths. This polymer can also be made using ring opening metathesis polymerization (ROMP) or nitroxide mediated coupling reactions, which can produce non-uniform chains

Purity: Min. 95%

Color and Shape: Powder

Ref: 3D-FP163582

Polyquaternium-1

CAS: 75345-27-6

Polyquaternium-1: a mild eye-safe preservative that inhibits microbes in multi-dose ophthalmic meds.

Formula: C₂₂H₄₈Cl₃N₃O₆

Purity: 95%

Color and Shape: Solid

Molecular weight: 556.99

Ref: TM-T20655

Polyquaternium 1

CAS: 75345-27-6

Formula: C₂₂H₄₈N₃O₆C₆H₁₂N·Cln·3Cl

Molecular weight: 450.64[98.17 35.45]n 3x35.45

Ref: 4Z-P-194001