CAS 7535-72-0

Z-Gly-Leu-NH2

Description:

Z-Gly-Leu-NH2, also known as Z-Glycyl-Leucine amide, is a peptide derivative characterized by its specific amino acid sequence and protective group. The "Z" denotes a benzyloxycarbonyl (Cbz) protecting group on the glycine residue, which enhances stability and solubility. This compound features a glycine (Gly) and leucine (Leu) amino acid sequence, with an amide (-NH2) group at the C-terminus, which can influence its biological activity and solubility. Z-Gly-Leu-NH2 is typically used in peptide synthesis and research, particularly in studies related to peptide hormones, neurotransmitters, and drug development. Its properties include being a white to off-white solid, soluble in polar solvents, and exhibiting stability under standard laboratory conditions. The presence of the amide group may also impart specific interactions in biological systems, making it of interest in pharmacological applications. Overall, Z-Gly-Leu-NH2 serves as a valuable compound in the field of biochemistry and medicinal chemistry.

Formula: C₁₆H₂₃N₃O₄

Synonyms:

• L-Leucinamide, N-[(phenylmethoxy)carbonyl]glycyl-
• Carbamicacid, [[(1-carbamoyl-3-methylbutyl)carbamoyl]methyl]-, benzyl ester
• Carbamic acid, [[(1-carbamoyl-3-methylbutyl)carbamoyl]methyl]-, benzyl ester,L-
• Leucinamide, N-carboxyglycyl-, benzyl ester, L-
• Benzyloxycarbonylglycyl-L-leucinamide
• N-(Benzyloxycarbonyl)glycyl-L-leucinamide
• N-Benzyloxycarbonylglycyl-L-leucineamide
• N-Carbobenzoxy-glycyl-leucine amide
• N-Carbobenzoxyglycyl-L-leucinamide

Z-Gly-Leu-NH2

CAS: 7535-72-0

Z-Gly-Leu-NH2 is a peptide that has been shown to have specificities against the bacteria Staphylococcus. It was obtained by the synthesis of a synthetic peptide with a sequence corresponding to the amino acid sequence of casein, which is a protein found in milk. The peptide contains four amino acids and has been shown to induce cytopathic effect in staphylococci, which are rod-shaped bacteria. This peptide also has high thermostability, which means it can be heated up to 100°C for 10 minutes without changing its activity. Z-Gly-Leu-NH2 is stable at pH 5 and is resistant to proteolytic degradation by subtilisin, making it an ideal candidate for use as a food additive.

Formula: C₁₆H₂₃N₃O₄

Purity: Min. 95%

Molecular weight: 321.37 g/mol

Ref: 3D-SGL-3037

Z-Gly-Leu-NH2

CAS: 7535-72-0

Z-Gly-Leu-NH2 is a synthetic peptide that has been designed to mimic the amino acid sequence of casein. It is a metalloendopeptidase inhibitor and can be used in the synthesis of proteins. Z-Gly-Leu-NH2 inhibits the activity of subtilisin, which is a proteolytic enzyme. The inhibition of subtilisin by Z-Gly-Leu-NH2 prevents the hydrolysis of peptide bonds in protein substrates. This inhibition leads to an increase in molecular weight and molecular weight distribution, as well as an increase in the number of high molecular weight peaks on chromatograms. This peptide also has serine protease inhibitory activity and can be used as a synthetic substrate for kinetic studies.

Formula: C₁₆H₂₃N₃O₄

Purity: Min. 95%

Molecular weight: 321.37 g/mol

Ref: 3D-FG111477