CAS 7536-58-5

N-tert-Butoxycarbonyl-L-aspartic acid β-benzyl ester

Description:

N-tert-Butoxycarbonyl-L-aspartic acid β-benzyl ester, commonly referred to as Boc-L-Asp(β-Bn) or by its CAS number 7536-58-5, is an amino acid derivative used primarily in peptide synthesis and organic chemistry. This compound features a tert-butoxycarbonyl (Boc) protecting group, which is commonly employed to protect the amino group during peptide synthesis, allowing for selective reactions at other functional groups. The β-benzyl ester moiety enhances the lipophilicity of the molecule, facilitating its incorporation into various organic reactions. N-tert-Butoxycarbonyl-L-aspartic acid β-benzyl ester is typically a white to off-white solid and is soluble in organic solvents such as dichloromethane and methanol, but less soluble in water. Its structure includes a carboxylic acid functional group, which can participate in further chemical transformations. The compound is valuable in the synthesis of peptides and other bioactive molecules, making it significant in pharmaceutical and biochemical research. Proper handling and storage are essential due to its potential reactivity and the need for specific conditions during synthesis.

Formula: C₁₆H₂₁NO₆

InChI: InChI=1/C16H21NO6/c1-16(2,3)23-15(21)17-12(14(19)20)9-13(18)22-10-11-7-5-4-6-8-11/h4-8,12H,9-10H2,1-3H3,(H,17,21)(H,19,20)/t12-/m0/s1

InChI key: InChIKey=SOHLZANWVLCPHK-LBPRGKRZSA-N

SMILES: C(OC(C[C@H](NC(OC(C)(C)C)=O)C(O)=O)=O)C1=CC=CC=C1

Synonyms:

• (2S)-2-[(2-Methylpropan-2-yl)oxycarbonylamino]-4-oxo-4-phenylmethoxybutanoic acid
• (2S)-4-(Benzyloxy)-2-[(tert-butoxycarbonyl)amino]-4-oxobutanoic acid
• (2S)-4-(benzyloxy)-2-[(tert-butoxycarbonyl)amino]-4-oxobutanoate
• (2S)-4-(benzyloxy)-2-[(tert-butoxycarbonyl)amino]-4-oxobutanoic acid (non-preferred name)
• (S)-2-tert-Butoxycarbonylaminosuccinic acid 4-benzyl ester
• (S)-4-(Benzyloxy)-2-[(tert-butoxycarbonyl)amino]-4-oxobutanoic acid
• 4-(Benzyloxy)-2-[(Tert-Butoxycarbonyl)Amino]-4-Oxobutanoic Acid (Non-Preferred Name)
• 4-Benzylhydrogen-N-(tert-butoxycarbonyl)-L-aspartat
• 4-benzyl hydrogen N-(tert-butoxycarbonyl)-L-aspartate
• <span class="text-smallcaps">L</span>-Aspartic acid, N-[(1,1-dimethylethoxy)carbonyl]-, 4-(phenylmethyl) ester
• Aspartic acid, N-carboxy-, 4-benzyl N-tert-butyl ester, <span class="text-smallcaps">L</span>-
• Aspartic acid, N-carboxy-, 4-benzyl N-tert-butyl ester, L-
• Boc-<span class="text-smallcaps">L</span>-Asp(OBn)-OH
• Boc-Asp(OBzl)-OH
• Boc-L-aspartic acid 4-benzyl ester
• Hydrogeno-N-(tert-butoxycarbonyl)-L-aspartate de 4-benzyle
• L-Aspartic acid, N-[(1,1-dimethylethoxy)carbonyl]-, 4-(phenylmethyl) ester
• N-(tert-Butoxycarbonyl)aspartic acid β-benzyl ester
• N-(tert-Butyloxycarbonyl)-<span class="text-smallcaps">L</span>-aspartic acid β-benzyl ester
• N-(tert-Butyloxycarbonyl)-L-aspartic acid β-benzyl ester
• N-(tert-Butyloxycarbonyl)-β-benzyl-<span class="text-smallcaps">L</span>-aspartic acid
• N-(tert-Butyloxycarbonyl)-β-benzyl-L-aspartic acid
• N-[(1,1-Dimethylethoxy)carbonyl]-<span class="text-smallcaps">L</span>-aspartic acid 4-(phenylmethyl) ester
• N-[(1,1-Dimethylethoxy)carbonyl]-L-aspartic acid 4-(phenylmethyl) ester
• N-tert-Butoxycarbonyl-<span class="text-smallcaps">L</span>-aspartic acid 4-benzyl ester
• N-tert-Butoxycarbonyl-<span class="text-smallcaps">L</span>-aspartic acid β-benzyl ester
• N-tert-Butoxycarbonyl-L-aspartic acid 4-benzyl ester
• N-tert-Butoxycarbonyl-L-aspartic acid β-benzyl ester
• N-tert.-Butoxycarbonyl-<span class="text-smallcaps">L</span>-aspartic acid 4-phenylmethyl ester
• hidrogeno-N-(terc-butoxicarbonil)-L-aspartato de 4-bencilo
• β-Benzyl N-tert-butoxycarbonylaspartate
• BOC-ASP(OBZL)
• BOC-BETA-BENZYLESTER L-ASPARTIC ACID
• N-ALPHA-T-BOC-L-ASPARTIC-BETA-BENZYL ESTER
• BOC-ASPARTIC ACID BETA-BENZYL ESTER
• BOC-L-ASPARTIC ACID B-BENZYL ESTER
• N-ALPHA-T-BUTOXYCARBONYL-L-ASPARTIC ACID BETA-BENZYL ESTER
• BOC-L-ASP(OBZL)-OH
• N-BOC-L-ASPARTIC ACID 4-BENZYL ESTER
• BOC-L-ASPARTIC ACID (OBZL)
• BOC-ASPARTIC ACID(OBZL)-OH
• BOC-L-ASP(BZL)-OH
• N-ALPHA-TERT-BUTYLOXYCARBONYL-L-ASPARTIC ACID BETA-BENZYL ESTER
• BOC-L-ASPARTIC ACID BETA-BENZYL ESTER
• BOC-L-ASP(OBZL)
• N-ALPHA-T-BOC-L-ASPARTIC ACID BETA-BENZYL ESTER
• 4-BENZYL N-(TERT-BUTOXYCARBONYL)-L-ASPARTATE

4-Benzyl N-(tert-Butoxycarbonyl)-L-aspartate

CAS: 7536-58-5

Formula: C₁₆H₂₁NO₆

Purity: >98.0%(T)

Color and Shape: White to Almost white powder to crystal

Molecular weight: 323.35

Ref: 3B-B1628

N-Boc-L-aspartic acid 4-benzyl ester, 98%

CAS: 7536-58-5

This Thermo Scientific Chemicals brand product was originally part of the Alfa Aesar product portfolio. Some documentation and label information may refer to the legacy brand. The original Alfa Aesar product / item code or SKU reference has not changed as a part of the brand transition to Thermo Sci

Formula: C₁₆H₂₁NO₆

Purity: 98%

Color and Shape: White, Powder

Molecular weight: 323.35

Ref: 02-B21758

Boc-Asp(OBzl)-OH

CAS: 7536-58-5

Bachem ID: 4000620.

Formula: C₁₆H₂₁NO₆

Purity: 98.1%

Color and Shape: White

Molecular weight: 323.35

Ref: 01-4000620

Boc-Asp(OBzl)-OH

CAS: 7536-58-5

Formula: C₁₆H₂₁NO₆

Purity: 98%

Color and Shape: Solid

Molecular weight: 323.3410

Ref: IN-DA0038GO

Boc-L-aspartic acid 4-benzyl ester

CAS: 7536-58-5

Boc-L-aspartic acid 4-benzyl ester (Boc-Asp(OBzl)-OH) is an aspartic acid derivative.

Formula: C₁₆H₂₁NO₆

Purity: 99.57%

Color and Shape: Solid

Molecular weight: 323.34

Ref: TM-T64335

Boc-Asp(OBzl)-OH

CAS: 7536-58-5

Formula: C₁₆H₂₁NO₆

Molecular weight: 323.35

Ref: 7W-GM3879

(2S)-2-Amino-4-(benzyloxy)-4-oxobutanoic acid, N-BOC protected

CAS: 7536-58-5

(2S)-2-Amino-4-(benzyloxy)-4-oxobutanoic acid, N-BOC protected

Formula: C₁₆H₂₁NO₆

Purity: 98%

Color and Shape: white solid

Molecular weight: 323.34g/mol

Ref: 54-OR46046

Boc-L-aspartic acid 4-benzyl ester, 10mM (in DMSO)

CAS: 7536-58-5

Boc-L-aspartic acid 4-benzyl ester, 10mM (in DMSO)

Purity: ≥98%

Molecular weight: 323.34g/mol

Ref: 54-BUP19105

Boc-Asp(OBzl)-OH

CAS: 7536-58-5

M03266 - Boc-Asp(OBzl)-OH

Formula: C₁₆H₂₁NO₆

Purity: 98%

Color and Shape: Solid, Crystalline Powder

Molecular weight: 323.345

Ref: 10-M03266

BOC-L-Aspartic Acid-4-Benzylester extrapure, 98%

CAS: 7536-58-5

Formula: C₁₆H₂₁NO₆

Purity: min. 98%

Color and Shape: White to off-white, Crystalline powder

Molecular weight: 323.34

Ref: SR-12202

Boc-Asp(OBzl)-OH

CAS: 7536-58-5

Boc-Asp(OBzl)-OH is a cyclic peptide analog with an amino acid sequence homologous to the natural substrate of soybean trypsin. It has been shown to inhibit thrombin by intramolecular hydrogen bonding. Boc-Asp(OBzl)-OH has also been used as a prodrug for the synthesis of other analogs, such as Asp(OBzl)-Bz-NH2, which inhibits human immunodeficiency virus type 1 (HIV-1) protease. This inhibitor has been found to be effective in vitro and in vivo against HIV-1 strains that are resistant to other protease inhibitors, such as saquinavir, indinavir, and ritonavir.

Formula: C₁₆H₂₁NO₆

Purity: Min. 95%

Molecular weight: 323.34 g/mol

Ref: 3D-BLD-2059