CAS 75369-61-8

5-Hydroxy-2-[[2-methyl-3-(trifluoromethyl)phenyl]amino]-3-pyridinecarboxylic acid

Description:

5-Hydroxy-2-[[2-methyl-3-(trifluoromethyl)phenyl]amino]-3-pyridinecarboxylic acid, with the CAS number 75369-61-8, is a chemical compound that features a pyridine ring substituted with a carboxylic acid and a hydroxyl group, along with an amino group linked to a phenyl ring that has a trifluoromethyl group. This structure suggests that the compound may exhibit both acidic and basic properties due to the presence of the carboxylic acid and amino functionalities. The trifluoromethyl group is known to enhance lipophilicity and can influence the compound's biological activity. The presence of multiple functional groups indicates potential for hydrogen bonding, which may affect solubility and reactivity. This compound may be of interest in pharmaceutical research, particularly in the development of drugs targeting specific biological pathways. Its unique structural features could also make it a candidate for studies in medicinal chemistry, where modifications to the molecule could lead to variations in efficacy and safety profiles.

Formula: C₁₄H₁₁F₃N₂O₃

InChI: InChI=1S/C14H11F3N2O3/c1-7-10(14(15,16)17)3-2-4-11(7)19-12-9(13(21)22)5-8(20)6-18-12/h2-6,20H,1H3,(H,18,19)(H,21,22)

InChI key: InChIKey=JSXNJGKWSWRIGA-UHFFFAOYSA-N

SMILES: N(C1=C(C(O)=O)C=C(O)C=N1)C2=C(C)C(C(F)(F)F)=CC=C2

Synonyms:

• 3-Pyridinecarboxylic acid, 5-hydroxy-2-[[2-methyl-3-(trifluoromethyl)phenyl]amino]-
• 5-Hydroxy Flunixin
• 5-Hydroxy-2-[[2-methyl-3-(trifluoromethyl)phenyl]amino]-3-pyridinecarboxylic Acid
• 5-Hydroxyflunixin

3-Pyridinecarboxylicacid, 5-hydroxy-2-[[2-methyl-3-(trifluoromethyl)phenyl]amino]-

CAS: 75369-61-8

Formula: C₁₄H₁₁F₃N₂O₃

Color and Shape: Solid

Molecular weight: 312.2439

Ref: IN-DA005Y03

5-Hydroxy Flunixin

CAS: 75369-61-8

Formula: C₁₄H₁₁F₃N₂O₃

Color and Shape: Off-White Solid

Molecular weight: 312.25

Ref: 4Z-F-662

5-hydroxy Flunixin

CAS: 75369-61-8

5-hydroxy Flunixin is a metabolite of the COX inhibitor flunixin .1

Formula: C₁₄H₁₁F₃N₂O₃

Color and Shape: Solid

Molecular weight: 312.248

Ref: TM-T37209

Flunixin-5-hydroxy

CAS: 75369-61-8

Color and Shape: Neat

Ref: 04-C13727100

Flunixin-5-hydroxy 100 µg/mL in Acetonitrile

CAS: 75369-61-8

Formula: C₁₄H₁₁F₃N₂O₃

Color and Shape: Single Solution

Molecular weight: 312.24

Ref: 04-A13727100AL-100

5-Hydroxy Flunixin (Contain 5% Flunixin)

CAS: 75369-61-8

Stability Hygroscopic
Applications The main metabolite of Flunixin.
References Odensvik, K., et al.: Am. J. Vet. Res., 56, 489 (1995), Ngoh, M.A., et al.: J. Agric. Food Chem., 51, 4701 (2003).

Formula: C₁₄H₁₁F₃N₂O₃

Color and Shape: Dark Orange

Molecular weight: 312.24

Ref: TR-H942420

5-Hydroxy flunixin

CAS: 75369-61-8

Flunixin is a nonsteroidal anti-inflammatory drug that is eliminated in the urine. The terminal half-life of flunixin and its metabolite, 5-hydroxyflunixin, are approximately 2 hours and 4 hours, respectively. Flunixin has a linear calibration curve with an R2 value of 0.9993. This drug can be quantified using liquid chromatography tandem mass spectrometry (LC-MS/MS) by preparing the sample with sodium carbonate to hydrolyze any ester groups to the corresponding acid form and then using LC-MS/MS to detect the parent compound and metabolite. The limit of detection for flunixin is 10 ng/mL; the limit of quantification is 20 ng/mL. The concentration of flunixin was found to be 0.14 ± 0.03 µg/mL in human food samples that were analyzed by this method.

Formula: C₁₄H₁₁F₃N₂O₃

Purity: Min. 95%

Color and Shape: Powder

Molecular weight: 312.24 g/mol

Ref: 3D-FH24012

5-Hydroxy Flunixin-d3 (Major)

Controlled Product

CAS: 75369-61-8

Applications 5-Hydroxy Flunixin-d3 Major is the main metabolite of Flunixin.
References Odensvik, K., et al.: Am. J. Vet. Res., 56, 489 (1995), Ngoh, M.A., et al.: J. Agric. Food Chem., 51, 4701 (2003).

Formula: C₁₄H₈D₃F₃N₂O₃

Color and Shape: Neat

Molecular weight: 315.26

Ref: TR-H942424

5-Hydroxy Flunixin

CAS: 75369-61-8

Formula: C₁₄H₁₁F₃N₂O₃

Molecular weight: 312.25

Ref: ST-EA-CP-F61006