N-Desmethyltramadol, with the CAS number 75377-45-6, is a chemical compound that is a metabolite of tramadol, a widely used analgesic. It is classified as an opioid and exhibits analgesic properties, although it is generally considered to be less potent than its parent compound, tramadol. The molecular structure of N-Desmethyltramadol includes a phenolic group and an amine, contributing to its pharmacological activity. This compound interacts with the central nervous system, primarily through mu-opioid receptors, and also influences the reuptake of neurotransmitters such as serotonin and norepinephrine, which can enhance its pain-relieving effects. N-Desmethyltramadol is of interest in pharmacology and toxicology due to its role in the metabolism of tramadol and its potential implications in drug testing and abuse. Its safety profile and side effects are similar to those of other opioids, necessitating careful consideration in clinical use. As with any opioid, there is a risk of dependence and misuse associated with N-Desmethyltramadol.

N-Desmethyltramadol

75377-45-6: N-Desmethyltramadol, with the CAS number 75377-45-6, is a chemical compound that is a metabolite of tramadol, a widely used analgesic. It is classified as an opioid and exhibits analgesic properties, although it is generally considered to be less potent than its parent compound, tramadol. The molecular structure of N-Desmethyltramadol includes a phenolic group and an amine, contributing to its pharmacological activity. This compound interacts with the central nervous system, primarily through mu-opioid receptors, and also influences the reuptake of neurotransmitters such as serotonin and norepinephrine, which can enhance its pain-relieving effects. N-Desmethyltramadol is of interest in pharmacology and toxicology due to its role in the metabolism of tramadol and its potential implications in drug testing and abuse. Its safety profile and side effects are similar to those of other opioids, necessitating careful consideration in clinical use. As with any opioid, there is a risk of dependence and misuse associated with N-Desmethyltramadol.

Applications A metabolite of Tramadol. Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package References Lintz, V.W., et al.: Arzneim.-Forsch./Drug Res., 31, II, 11, 1932 (1981)

CAS 75377-45-6

N-Desmethyltramadol

rac N-Desmethyl Tramadol

Ref: TR-D294700