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CAS 7542-37-2

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Paromomycin

Description:
Paromomycin is an aminoglycoside antibiotic primarily used to treat infections caused by certain parasites and bacteria. It is derived from the bacterium Streptomyces griseus and is particularly effective against protozoan infections such as leishmaniasis and amebiasis. Paromomycin works by binding to the 30S ribosomal subunit of bacteria, inhibiting protein synthesis, which ultimately leads to bacterial cell death. The compound is characterized by its relatively low toxicity compared to other aminoglycosides, making it suitable for use in specific populations, including pregnant women for certain infections. Paromomycin is typically administered orally or intramuscularly, depending on the condition being treated. Its solubility in water allows for easy formulation in various pharmaceutical preparations. However, it is important to monitor for potential side effects, including gastrointestinal disturbances and nephrotoxicity, especially in patients with pre-existing kidney conditions. Overall, Paromomycin remains a valuable therapeutic agent in the treatment of specific infectious diseases.
Formula:C23H45N5O14
InChI:InChI=1S/C23H45N5O14/c24-2-7-13(32)15(34)10(27)21(37-7)41-19-9(4-30)39-23(17(19)36)42-20-12(31)5(25)1-6(26)18(20)40-22-11(28)16(35)14(33)8(3-29)38-22/h5-23,29-36H,1-4,24-28H2/t5-,6+,7+,8-,9-,10-,11-,12+,13-,14-,15-,16-,17-,18-,19-,20-,21-,22-,23+/m1/s1
InChI key:InChIKey=UOZODPSAJZTQNH-LSWIJEOBSA-N
SMILES:O([C@H]1[C@H](O[C@H]2[C@H](O)[C@H](O[C@H]3O[C@@H](CN)[C@@H](O)[C@H](O)[C@H]3N)[C@@H](CO)O2)[C@@H](O)[C@H](N)C[C@@H]1N)[C@H]4O[C@H](CO)[C@@H](O)[C@H](O)[C@H]4N
Synonyms:
  • (1R,2R,3S,4R,6S)-4,6-Diamino-2-{[3-O-(2,6-diamino-2,6-dideoxy-beta-L-idopyranosyl)-beta-D-ribofuranosyl]oxy}-3-hydroxycyclohexyl 2-amino-2-deoxy-alpha-D-glucopyranoside
  • 231-423-0
  • <span class="text-smallcaps">D</smallcap>-Streptamine, O-2,6-diamino-2,6-dideoxy-β-<smallcap>L</smallcap>-idopyranosyl-(1→3)-O-β-<smallcap>D</smallcap>-ribofuranosyl-(1→5)-O-[2-amino-2-deoxy-α-<smallcap>D</span>-glucopyranosyl-(1→4)]-2-deoxy-
  • <span class="text-smallcaps">D</smallcap>-Streptamine, O-2-amino-2-deoxy-α-<smallcap>D</smallcap>-glucopyranosyl-(1→4)-O-[O-2,6-diamino-2,6-dideoxy-β-<smallcap>L</smallcap>-idopyranosyl-(1→3)-β-<smallcap>D</span>-ribofuranosyl-(1→5)]-2-deoxy-
  • Aminosidin
  • Aminosidine
  • Aminosidine I
  • Amminosidin
  • Antibiotic 2230D
  • Antibiotic 503-3
  • See more synonyms
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Found 4 products.
  • Paromomycin Sulfate
    TCI
    + Info

    Paromomycin Sulfate

    CAS:
    Formula:C23H45N5O14·xH2SO4
    Purity:>92.0%(HPLC)
    Color and Shape:White to Almost white powder to crystal

    Ref: 3B-P2092

    1g
    45.00€
    5g
    139.00€
  • Paromomycin Deuterated Acetic Acid Salt
    TRC
    + Info

    Paromomycin Deuterated Acetic Acid Salt

    Controlled Product
    CAS:
    <p>Applications Paromomycin Deuterated Acetic Acid Salt is the isotope labelled analog of Paromomycin Sulfate. Paromomycin Sulfate is an aminogycoside antibiotic designed to fight intestinal infections such as cryptosporidiosis, amoebiasis, and leishmaniasis. Its antiprotozoal activity makes it an effecive histomonostatic feed additive in turkey poults experimentally infected with Histomonas meleagridis.<br>References Rehg, J.E. et al.: J. Infect. Dis., 170, 934 (1994); Fong, D. et al.: Am. J. Trop. Med. Hyg., 51, 758 (1994); Hafez, H.M. et al.: Arch. Anim. Nut., 64, 77 (2010);<br></p>
    Formula:C23H45N5O14•5(CH3COOH)forundeuterated
    Color and Shape:Neat
    Molecular weight:615.63

    Ref: TR-P205653

    1mg
    326.00€
    10mg
    2,198.00€
  • Aminosidine
    Biosynth
    + Info

    Aminosidine

    CAS:
    <p>Aminosidine is a nucleoside analogue that inhibits the HIV-1 reverse transcriptase and the integrase, which are enzymes involved in viral DNA synthesis. Aminosidine is active against Leishmania spp., but not against bacteria. Aminosidine has been shown to be effective in experimental models of human bowel disease and in patients with inflammatory bowel disease. It was also found to be active against wild-type strains of human immunodeficiency virus type 1, but not resistant mutants. The mechanism of action is the inhibition of cellular mitochondrial membrane potential.</p>
    Purity:Min. 95%

    Ref: 3D-OA11590

    1g
    To inquire
  • Neomycin EP Impurity E
    Standalix
    + Info

    Neomycin EP Impurity E

    CAS:
    Formula:C23H45N5O14
    Molecular weight:615.63

    Ref: ST-EA-CP-N53012

    10mg
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    25mg
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    50mg
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    100mg
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