CAS 75444-65-4

Pirenperone

Description:

Pirenperone is a chemical compound primarily recognized for its role as an atypical antipsychotic agent. It belongs to the class of compounds known as serotonin receptor antagonists, specifically targeting the 5-HT2A receptor. This compound is characterized by its ability to modulate neurotransmitter activity in the brain, which contributes to its therapeutic effects in managing psychiatric disorders. Pirenperone exhibits a relatively low affinity for dopamine receptors, distinguishing it from many traditional antipsychotics. Its chemical structure includes a piperazine moiety, which is common in many pharmacologically active compounds. The substance is typically administered in a clinical setting and has been studied for its potential effects on mood and anxiety disorders. Additionally, pirenperone's pharmacokinetic properties, such as absorption, distribution, metabolism, and excretion, are crucial for understanding its efficacy and safety profile. As with any pharmacological agent, potential side effects and interactions with other medications should be considered when evaluating its use in therapeutic contexts.

Formula: C₂₃H₂₄FN₃O₂

InChI: InChI=1S/C23H24FN3O2/c1-16-20(23(29)27-12-3-2-4-21(27)25-16)11-15-26-13-9-18(10-14-26)22(28)17-5-7-19(24)8-6-17/h2-8,12,18H,9-11,13-15H2,1H3

InChI key: InChIKey=HXCNRYXBZNHDNE-UHFFFAOYSA-N

SMILES: O=C1N2C(=NC(C)=C1CCN3CCC(C(=O)C4=CC=C(F)C=C4)CC3)C=CC=C2

Synonyms:

• 3-(2-(4-(p-Fluorobenzoyl)piperidino)ethyl)-2-methyl-4H-pyrido(1,2-a)pyrimidin-4-one
• 3-[2-[4-(4-Fluorobenzoyl)-1-piperidinyl]ethyl]-2-methyl-4H-pyrido[1,2-a]pyrimidin-4-one
• 3-{2-[4-(4-fluorobenzoyl)piperidin-1-yl]ethyl}-2-methyl-4H-pyrido[1,2-a]pyrimidin-4-one
• 4H-Pyrido(1,2-a)pyrimidin-4-one, 3-(2-(4-(4-fluorobenzoyl)-1-piperidinyl)ethyl)-2-methyl-
• Pirenperona
• Pirenperona [INN-Spanish]
• Pirenperone [USAN:INN:BAN]
• Pirenperonum
• Pirenperonum [INN-Latin]
• R-47,465
• Unii-Y9Fmc4513X

Pirenperone

CAS: 75444-65-4

Pirenperone

Purity: ≥98%

Molecular weight: 393.45g/mol

Ref: 54-BUP00988

Pirenperone

CAS: 75444-65-4

Formula: C₂₃H₂₄FN₃O₂

Molecular weight: 393.45

Ref: 7W-GL3065

Pirenperone

CAS: 75444-65-4

Pirenperone is a putative 5-HT2 receptor antagonist with the central antiserotonergic and antidopaminergic action.

Formula: C₂₃H₂₄FN₃O₂

Purity: 99.2%

Color and Shape: Solid

Molecular weight: 393.45

Ref: TM-T2599

Pirenperone

Controlled Product

CAS: 75444-65-4

Applications Pirenperone is a 5-HT2 serotonin receptor antagonist. Pirenperone also increases phosphorylation in human glioma cells by inhibiting cellular gap junctions.
References Warchal, S., et.al.: Bioorganic & Medicinal Chemistry. (2019); Yeo, J.Y., et.al: PLoS One. 14(9), 222-326. (2019)

Formula: C₂₃H₂₄FN₃O₂

Color and Shape: Neat

Molecular weight: 393.45

Ref: TR-P508505

Pirenperone

CAS: 75444-65-4

Serotonin receptor antagonist

Formula: C₂₃H₂₄FN₃O₂

Purity: Min. 95%

Molecular weight: 393.45 g/mol

Ref: 3D-FP172697