CAS 75451-07-9

Ethyl 10,11-dihydro-4-methoxydibenz[b,f][1,4]oxazepine-8-carboxylate

Description:

Ethyl 10,11-dihydro-4-methoxydibenz[b,f][1,4]oxazepine-8-carboxylate, with the CAS number 75451-07-9, is a chemical compound that belongs to the class of dibenzoxazepines. This substance features a complex bicyclic structure that includes an oxazepine ring, which is characterized by the presence of both nitrogen and oxygen atoms within the ring system. The compound is typically recognized for its potential pharmacological properties, which may include effects on the central nervous system. Its methoxy and ethyl ester functional groups contribute to its solubility and reactivity, making it of interest in medicinal chemistry. The presence of the carboxylate group suggests potential for further chemical modifications, which could enhance its biological activity or alter its pharmacokinetic properties. As with many organic compounds, its stability, reactivity, and interactions with biological systems are influenced by its molecular structure, making it a subject of study in drug development and synthesis.

Formula: C₁₇H₁₇NO₄

InChI: InChI=1/C17H17NO4/c1-3-21-17(19)11-7-8-14-13(9-11)18-10-12-5-4-6-15(20-2)16(12)22-14/h4-9,18H,3,10H2,1-2H3

SMILES: CCOC(=O)c1ccc2c(c1)NCc1cccc(c1O2)OC

Synonyms:

• Az-1355
• 10,11-Dihydro-4-methoxydibenz[b,f][1,4]oxazepine-8-carboxylic acid ethyl ester
• Ethyl 4-Methoxy-10,11-Dihydrodibenzo[B,F][1,4]Oxazepine-8-Carboxylate
• Dibenz[b,f][1,4]oxazepine-8-carboxylic acid, 10,11-dihydro-4-methoxy-, ethyl ester
• (NSC 364889
• 11,12-dihydro-4-methoxydibenz(b,f)(1,4)oxazepine-8-carboxylate

AZ-1355

CAS: 75451-07-9

AZ-1355

Purity: ≥98%

Molecular weight: 299.32g/mol

Ref: 54-BUP08809

AZ-1355

CAS: 75451-07-9

AZ-1355 is a novel, orally bioavailable, small molecule inhibitor of collagen-specific proteinase (MMP-1) that has been shown to be effective in preventing the development of cerebral amyloidosis in hamsters. AZ-1355 is orally bioavailable and penetrates the blood brain barrier, thus reducing the amount of MMP-1 that can enter the brain. This drug has also been shown to reduce cardiac collagen deposition and improve endothelial function. AZ-1355 has not been tested on humans or animals for its potential toxicity, but it does have a toxic profile in vitro. This drug has also been shown to have damaging effects on platelets and cause death in cultured cells.

Formula: C₁₇H₁₇NO₄

Purity: Min. 95%

Molecular weight: 299.32 g/mol

Ref: 3D-ADA45107

AZ-1355

CAS: 75451-07-9

AZ-1355 is a novel dibenzoxepine derivative with lipid-lowering properties.

Formula: C₁₇H₁₇NO₄

Purity: 99.81%

Color and Shape: Solid

Molecular weight: 299.32

Ref: TM-T13563