CAS 75520-89-7

N-[(7R)-1,2,3,10-tetramethoxy-9-oxo-5,6,7,9-tetrahydrobenzo[a]heptalen-7-yl]acetamide

Description:

N-[(7R)-1,2,3,10-tetramethoxy-9-oxo-5,6,7,9-tetrahydrobenzo[a]heptalen-7-yl]acetamide, with the CAS number 75520-89-7, is a complex organic compound characterized by its unique structural features, including a benzo[a]heptalene core and multiple methoxy groups. This compound exhibits a chiral center, indicated by the (7R) configuration, which can influence its biological activity and interactions. The presence of the acetamide functional group suggests potential for hydrogen bonding, which may enhance solubility in polar solvents. The methoxy groups contribute to the compound's lipophilicity, potentially affecting its pharmacokinetic properties. Additionally, the keto group (9-oxo) may play a role in reactivity and stability. Overall, this compound's intricate structure and functional groups suggest it may have interesting applications in medicinal chemistry, particularly in the development of pharmaceuticals or as a research tool in biochemical studies. However, specific biological activities and applications would require further investigation through empirical studies.

Formula: C₂₂H₂₅NO₆

InChI: InChI=1/C22H25NO6/c1-12(24)23-16-8-6-13-10-19(27-3)21(28-4)22(29-5)20(13)14-7-9-18(26-2)17(25)11-15(14)16/h7,9-11,16H,6,8H2,1-5H3,(H,23,24)/t16-/m1/s1

SMILES: CC(=N[C@@H]1CCc2cc(c(c(c2c2ccc(c(=O)cc12)OC)OC)OC)OC)O

(R)-Colchicine

CAS: 75520-89-7

Formula: C₂₂H₂₅NO₆

Molecular weight: 399.45

Ref: 4Z-C-1520

(R)-Colchicine

Controlled Product

CAS: 75520-89-7

Applications The R-enantiomer of Colchicine (C640000). An antimitotic agent that disrupts microtubles by binding to tubulin and preventing its polymerization. Stimulates the intrinsic GTPase activity of tubulin. Induces apoptosis in several normal and tumor cell lines and activates the JNK/SAPK signaling pathway.
Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package
References Lunduena, R.F., et al.: Curr. Opin. Cell Biol., 4, 53 (1992), Ceccatelli, S., et al.: Neuroreport, 8, 3779 (1997), Want, T.H., et al.: J. Biol. Chem., 273, 4928 (1998), Andreu, J.M., et al.: Biochemistry, 37, 8356 (1998), Jordan, A., et al.: Med. Res. Rev., 18, 259 (1998),

Formula: C₂₂H₂₅NO₆

Color and Shape: Neat

Molecular weight: 399.44

Ref: TR-C640001

(R)-Colchicine

CAS: 75520-89-7

Formula: C₂₂H₂₅NO₆

Molecular weight: 399.44

Ref: ST-EA-CP-C33018