CAS 75536-04-8

Moxonidine Hydrochloride

Description:

Moxonidine hydrochloride is a medication primarily used as an antihypertensive agent, belonging to the class of imidazoline receptor agonists. It functions by selectively stimulating I1-imidazoline receptors in the central nervous system, leading to a reduction in sympathetic outflow and a subsequent decrease in blood pressure. The substance is typically presented as a white to off-white crystalline powder, which is soluble in water and exhibits a pH range that is generally neutral. Moxonidine hydrochloride is characterized by its relatively low bioavailability when administered orally, necessitating careful dosage management. The drug is often prescribed for the treatment of essential hypertension and may be used in combination with other antihypertensive medications. Common side effects can include dry mouth, fatigue, and dizziness, reflecting its central nervous system activity. As with any medication, it is important to consider contraindications and potential interactions with other drugs. Overall, moxonidine hydrochloride represents a unique approach to managing high blood pressure through its specific receptor interactions.

Formula: C₉H₁₄ClN₅OHCl

InChI: InChI=1/C9H14ClN5O.ClH/c1-9(15-8-11-3-4-12-8)13-6(10)5-7(14-9)16-2;/h5,14H,3-4H2,1-2H3,(H2,11,12,15);1H

SMILES: CC1(N=C(C=C(N1)OC)Cl)NC1=NCCN1.Cl

Synonyms:

• 4-Chloro-N-(4,5-Dihydro-1H-Imidazol-2-yl)-6-Methoxy-2-Methyl-3H-pyrimidin-2-amine Hydrochloride
• Moxonidine HCL
• Bdf-5895 Hcl
• 4-Chloro-6-Methoxy-2-Methyl-5-(2-Imidazolin-2-YL)Aminopyrimidine HCL
• 4-Chloro-N-(4,5-Dihydro-1H-Imidazol-2-YL)-6-Methoxy-2-Methyl-5-Pyrimidinamine Hydrochloride
• 2-Pyrimidinamine, 4-chloro-N-(4,5-dihydro-1H-imidazol-2-yl)-6-methoxy-2-methyl-, hydrochloride
• Moxonidine hydrochloride CP
• Moxonidin hydrochloride

Moxonidine (hydrochloride)

CAS: 75536-04-8

Formula: C₉H₁₃Cl₂N₅O

Molecular weight: 278.1384

Ref: IN-DA00G3P6

Moxonidine hydrochloride

CAS: 75536-04-8

Moxonidine Hydrochloride: selective I1 imidazoline receptor agonist, stronger than α2-AR; lowers blood pressure; central action.

Formula: C₉H₁₃Cl₂N₅O

Color and Shape: Solid

Molecular weight: 278.14

Ref: TM-T40869

Moxonidine HCl - Bio-X ™

CAS: 75536-04-8

Moxonidine is an imidazoline/α-2 receptor agonist that is used to treat hypertension. This drug binds to the imidazoline receptor and to alpha-2 adrenoreceptors to reduce arterial blood pressure and systemic vascular resistance. Moxonidine also has effects on other physiological systems such as locomotor activity and autonomic nervous system functions.

Formula: C₉H₁₂ClN₅O•HCl

Purity: (%) Min. 95%

Color and Shape: Powder

Molecular weight: 278.14 g/mol

Ref: 3D-BM164613

Moxonidine HCl

CAS: 75536-04-8

α1 and α2 receptor agonist; imidazoline receptor ligand; anti-hypertensive

Formula: C₉H₁₂ClN₅O·HCl

Purity: Min. 95%

Color and Shape: White Powder

Molecular weight: 278.14 g/mol

Ref: 3D-FM26096

4-CHLORO-N-(4,5-DIHYDRO-1H-IMIDAZOL-2-YL)-6-METHOXY-2-METHYLPYRIMIDIN-5-AMINE HCL

CAS: 75536-04-8

Formula: C₉H₁₃Cl₂N₅O

Purity: 95.0%

Molecular weight: 278.14

Ref: 10-F533677