CAS 75539-79-6

N-cbz-D-phe-phe-gly

Description:

N-Cbz-D-Phe-Phe-Gly, also known by its CAS number 75539-79-6, is a synthetic peptide that features a combination of amino acids, specifically phenylalanine (Phe) and glycine (Gly), with a carbobenzyloxy (Cbz) protecting group on the D-phenylalanine residue. This compound is characterized by its white to off-white solid form and is soluble in organic solvents such as dimethyl sulfoxide (DMSO) and methanol, but generally insoluble in water. The presence of the Cbz group provides stability and protects the amino group during peptide synthesis, making it useful in various biochemical applications, including peptide synthesis and drug development. The stereochemistry of the D-phenylalanine is significant, as it can influence the biological activity and interactions of the peptide. N-Cbz-D-Phe-Phe-Gly can be utilized in research settings, particularly in studies related to peptide behavior, receptor binding, and the development of therapeutic agents. Proper handling and storage conditions are essential to maintain its integrity and effectiveness in experimental applications.

Formula: C₂₈H₂₉N₃O₆

InChI: InChI=1/C28H29N3O6/c32-25(33)18-29-26(34)23(16-20-10-4-1-5-11-20)30-27(35)24(17-21-12-6-2-7-13-21)31-28(36)37-19-22-14-8-3-9-15-22/h1-15,23-24H,16-19H2,(H,29,34)(H,30,35)(H,31,36)(H,32,33)/t23-,24+/m0/s1

Synonyms:

• Z-D-Phe-Phe-Gly-OH
• N-[(benzyloxy)carbonyl]-D-phenylalanyl-L-phenylalanylglycine

Z-D-Phe-Phe-Gly-OH

CAS: 75539-79-6

A high level of inhibition of virus replication was obtained with this peptide, which resembles a region of a viral polypeptide.

Formula: C₂₈H₂₉N₃O₆

Purity: > 99%

Color and Shape: White Powder

Molecular weight: 503.56

Ref: 01-4015768

Virus Replication Inhibiting Peptide

CAS: 75539-79-6

The virus replication-inhibiting peptide is a fatty acid that inhibits the replication of viruses. It has been shown to inhibit the growth of the bacteria Stenotrophomonas maltophilia and other bacteria, which causes infectious diseases. The peptide also has a diagnostic use for detecting viral infections in cells. The peptide was found to up-regulate genes in response to infection by pandemic influenza, which may be due to its ability to bind receptors on cells and also interfere with inflammatory responses. The virus replication-inhibiting peptide has been shown to be effective against influenza virus and other viruses, as well as against chronic inflammatory diseases such as lung damage caused by β-amino acids.

Formula: C₂₈H₂₉N₃O₆

Purity: Min. 95%

Molecular weight: 503.55 g/mol

Ref: 3D-PVI-4092

Z-D-Phe-Phe-Gly-OH

CAS: 75539-79-6

Z-D-Phe-Phe-Gly-OH is a lysosomal carboxypeptidase that hydrolyzes peptides at the C terminus of proteins. It has a wide substrate specificity and can hydrolyze Z-D-Phe-Phe-Gly, Z-Arg-Lys, and L-Arg. This enzyme has been shown to have ion exchange chromatography activity. The elution profile for this enzyme on a sephadex G-100 column was found to have an optimum pH of 7.5 and elutes at a salt concentration of 0.5M NaCl. Carboxypeptidases are enzymes that cleave at the C terminus of proteins to produce smaller peptides or amino acids. They are involved in digestion, blood clotting, and cell signaling processes.

Formula: C₂₈H₂₉N₃O₆

Purity: Min. 95%

Color and Shape: White Off-White Powder

Molecular weight: 503.55 g/mol

Ref: 3D-FP110429