CAS 75575-02-9

Androsta-1,4-diene-17-carboxylic acid, 6-fluoro-11-hydroxy-16,17-[(1-methylethylidene)bis(oxy)]-3-oxo-, (6α,11β,16α,17α)-

Description:

Androsta-1,4-diene-17-carboxylic acid, 6-fluoro-11-hydroxy-16,17-[(1-methylethylidene)bis(oxy)]-3-oxo-, (6α,11β,16α,17α)-, identified by CAS number 75575-02-9, is a synthetic steroid derivative with specific structural features that contribute to its biological activity. This compound contains a steroid backbone characterized by a fused four-ring structure typical of androgens, with modifications including a carboxylic acid group at the C-17 position and a fluoro substituent at the C-6 position. The presence of hydroxy groups and ether linkages enhances its potential for interaction with biological targets, particularly in the context of hormone receptor modulation. Its stereochemistry, denoted by the (6α,11β,16α,17α) configuration, indicates specific spatial arrangements of substituents that can influence its pharmacological properties. Such compounds are often investigated for their potential therapeutic applications, including anti-inflammatory and anabolic effects, although their safety and efficacy profiles require thorough evaluation in clinical settings.

Formula: C₂₃H₂₉FO₆

InChI: InChI=1S/C23H29FO6/c1-20(2)29-17-9-13-12-8-15(24)14-7-11(25)5-6-21(14,3)18(12)16(26)10-22(13,4)23(17,30-20)19(27)28/h5-7,12-13,15-18,26H,8-10H2,1-4H3,(H,27,28)/t12-,13-,15-,16-,17+,18+,21-,22-,23-/m0/s1

InChI key: InChIKey=VHPPNTCHLBALLQ-OXHRMPJJSA-N

SMILES: C(O)(=O)[C@]12[C@]3(C)[C@@](C[C@]1(OC(C)(C)O2)[H])([C@]4([C@]([C@@H](O)C3)([C@]5(C)C([C@@H](F)C4)=CC(=O)C=C5)[H])[H])[H]

Synonyms:

• Androsta-1,4-diene-17-carboxylic acid, 6-fluoro-11-hydroxy-16,17-[(1-methylethylidene)bis(oxy)]-3-oxo-, (6α,11β,16α,17α)-
• 6bH-Naphth[2′,1′:4,5]indeno[1,2-d][1,3]dioxole, androsta-1,4-diene-17-carboxylic acid deriv.

(6a,11b,16a,17a)-6-fluoro-11-hydroxy-16,17-[(1-methylethylidene)bis(oxy)]-3-oxo-androsta-1,4-diene-17-carboxylic Acid

Controlled Product

CAS: 75575-02-9

Applications (6α,11β,16α,17α)-6-fluoro-11-hydroxy-16,17-[(1-methylethylidene)bis(oxy)]-3-oxo-androsta-1,4-diene-17-carboxylic Acid is a fluorosteroid which was prepared and used in the study of hormone pharmacology and tested for androgenic, anabolic, antiandrogenic, gestagenic, estrogenic, antiestrogenic thymolytic, antiinflammatory, and mineralocorticoid activities.
References Gusarova, T. I., Khimiko-Farmatsevticheskii Zhurnal, 14, 39-42, (1980)

Formula: C₂₃H₂₉FO₆

Color and Shape: Neat

Molecular weight: 420.47

Ref: TR-F401790

Flunisolide-17-Carboxylic Acid

CAS: 75575-02-9

Formula: C₂₃H₂₉FO₆

Molecular weight: 420.5

Ref: ST-EA-CP-F74002