CAS 75621-03-3

3-[(3-Cholamidopropyl)dimethylammonio]-1-propanesulfonate

Description:

3-[(3-Cholamidopropyl)dimethylammonio]-1-propanesulfonate, commonly known as CHAPS, is a zwitterionic detergent widely used in biochemistry and molecular biology. It features a hydrophilic sulfonate group and a hydrophobic cholamine tail, which allows it to solubilize membrane proteins while maintaining their functional integrity. CHAPS is particularly valued for its ability to disrupt lipid bilayers and facilitate the extraction of proteins from cellular membranes without denaturing them. It is soluble in water and exhibits good stability across a range of pH levels, making it suitable for various biochemical applications, including protein purification and electrophoresis. Additionally, CHAPS is known for its low toxicity and minimal interference with enzymatic assays, which enhances its utility in laboratory settings. Its zwitterionic nature helps maintain protein structure and activity, making it an essential tool in studies involving membrane proteins and other sensitive biomolecules.

Formula: C₃₂H₅₈N₂O₇S

InChI: InChI=1/C32H58N2O7S/c1-21(8-11-29(38)33-14-6-15-34(4,5)16-7-17-42(39,40)41)24-9-10-25-30-26(20-28(37)32(24,25)3)31(2)13-12-23(35)18-22(31)19-27(30)36/h21-28,30,35-37H,6-20H2,1-5H3,(H-,33,38,39,40,41)/t21-,22+,23-,24-,25+,26+,27-,28+,30+,31+,32-/m1/s1

InChI key: InChIKey=UMCMPZBLKLEWAF-BCTGSCMUSA-N

SMILES: O[C@H]1[C@]2([C@]3([C@@](C)([C@@]([C@@H](CCC(NCCC[N+](CCCS(=O)(=O)[O-])(C)C)=O)C)(CC3)[H])[C@@H](O)C[C@@]2([C@]4(C)[C@](C1)(C[C@H](O)CC4)[H])[H])[H])[H]

Synonyms:

• 1-Propanaminium, N,N-dimethyl-N-(3-sulfopropyl)-3-[[(3α,5β,7α,12α)-3,7,12-trihydroxy-24-oxocholan-24-yl]amino]-, inner salt
• 3-((3-Cholamidopropyl)Dimethylammonio)Propanesulfonate
• 3-((3-Cholamidopropyl)Dimethylammonium)-1-Propanesulfonate
• 3-[(-3-Cholamidopropyl)-dimethylammonio]-1-propanesulfonate
• 3-[(3-Chloromidopropyl)dimethylammonio]-1-propanesulfonate
• 3-[(3-Cholamidopropyl)Dimethylammonio]-1-Propane Sulphonate
• 3-[(3-Cholamidopropyl)dimethylammonio]-1-propanesulphonate
• 3-[Dimethyl(3-{[(3Alpha,5Beta,7Alpha,12Alpha)-3,7,12-Trihydroxy-24-Oxocholan-24-Yl]Amino}Propyl)Ammonio]Propane-1-Sulfonate
• CHAPS 3-[(3-Cholamidopropyl)dimethylammonio]-1-propanesulfonate
• CHAPS Solution
• Chaps
• Cholane, 1-propanaminium deriv.
• Nonyl Acrylate
• MEDIABAG ST FOR 3375 ML BPW
• BRADFORD REAGENT BIOTECHNOLOGY GRADE
• 3-[(3-CHOLAMIDOPROPYL)DIMETHYLAMMONIO]PROPANESULFONAT(CHAPS)
• N-[3-(3-Sulfonatopropyldimethylaminio)propyl]-3α,7α,12α-trihydroxy-5β-cholan-24-amide
• 3-(3-(cholamidopropyl)dimethyl
• N,N-DiMethyl-N-(3-sulfopropyl)-3-[[(3α,5β,7α,12α)-3,7,12-trihydroxy-
• CHAPS 100 mM solution
• 3-cholamidopropyl)dimethyl-ammonio]-1-propanesulfonate)
• CHAPS (3-((3-CHOLAMIDOPROPYL)DIMETHYLAMMONIO)PROPANESULFONATE)
• 1-Propanaminium, N,N-dimethyl-N-(3-sulfopropyl)-3-(3.alpha.,5.beta.,7.alpha.,12.alpha.)-3,7,12-trihydroxy-24-oxocholan-24-ylamino-, inner salt
• Chaps3-[3-(Cholamidopropyl)Dimethylamonio]-1-Propanesulfonate
• CHAPS,CRYSTALLINEPOWDER,ULTRAPURE
• 3-[(3-Cholamidopropyl)dimethylammonio]-1-propane sulfonate ,98%
• TREND
• CHAPS, >=99%
• Cholamidopropyl)dimethylammonio]-1-propanesulfonate
• CHAPS Vetec(TM) reagent grade, 96%
• 3-[(3-Cholanidopropyl)dimethylammonio]-1-propanesulfonate
• 3-[(3-Cholamidopropyl)dimethylammonio]propanesulfonic acid
• CHAPS ELECTROPHORESIS REAGENT
• 3-((3-((4R)-4-((10S,13R,17R)-10,13-DiMethylhexadecahydro-1H-cyclopenta[a]phenanthren-17-yl)pentanaMido)propyl)diMethylaMMonio)propane-1-sulfonate
• MEDIABAG ST FOR 450ML BPW 10 X10 ST
• N,N-Dimethyl-N-(3-sulfonatopropyl)-3-[[3α,7α,12α-trihydroxy-24-oxo-5β-cholan-24-yl]amino]-1-propaneaminium
• CHAPS, 98+%
• CHAPS,HighPurity
• 3-[(3-cholaMidopropyl)diMethylaMMonio]propanesulfonate(CHAPS)
• SMMP MEDIUM CONC.
• CHAPS, Molecular Biology Grade
• CHAPS extrapure
• 3-((3-Cholamidopropy
• 3-((3-Cholamidopropyl)dimethylammonium)-1-propanesulfonate (CHAPS)
• CHAPS-SOL GRADE
• 24-oxocholan-24-yl]aMino]-1-propanaMiniuM Inner Salt
• CHAPS buffer
• N,N-Dimethyl-N-(3-sulfonatopropyl)-3-[(3α,7α,12α-trihydroxy-24-oxo-5β-cholan-24-yl)amino]propylaminium
• TSA PETRI 9CM
• 3-[(3-cholamidopropyl)dimethylammonio]propane-1-sulfonate
• N,N-Dimethyl-N-(3-sulfopropyl)-3-[[(3a,5,7a,12a)-3,7,12-trihydroxy-24-oxocholan-24-yl]amino]-1-propanaminium Inner Salt
• 3-[(3-CHOLAMIDOPROPYL)DIMETHYLAMMONIO]-1-PROPANE SULPHONATE (ULTRAPURE)
• MEDIABAG ST FOR 4000 ML BPW
• 3-(3-CHOLAMIDOPROPYL)DIMETHYL-AMMONIO-1-PROPANESULFONATE RESEARCH
• 3-[(3-Cholamidopropyl)dimethylammonio]-1-propanesulphonate (Ultrapure) >99.0%

3-[(3-Cholamidopropyl)dimethylammonio]-1-propanesulfonate

CAS: 75621-03-3

Formula: C₃₂H₅₈N₂O₇S

Purity: >97.0%(N)

Color and Shape: White to Almost white powder to crystal

Molecular weight: 614.88

Ref: 3B-C1578

CHAPS 10% solution, sterile-filtered

CAS: 75621-03-3

Molecular weight: 614.8800048828125

Ref: 10-F546993

CHAPS, Electrophoresis Grade

CAS: 75621-03-3

CHAPS is often used as a detergent in the solubilization and purification of membrane proteins for several advantageous reasons. CHAPS detergent is non-denaturing to membrane proteins, can solubilize proteins, disaggregate protein-protein interactions. CHAPS is also useful in ion exchange chromatography and isoelectric focusing as it is zwitterionic and does not exhibit a net charge between pH 2 to 12. It is suitable for isolation of membrane proteins with the following features such as sufficient protein solubilization capability, no denaturing or inactivation of proteins, no interference with protein activities, no precipitation at 4°C, appropriate critical micelle concentrations (CMC) and micelle size, no absorption in the UV region, no toxicity and availability of detergent detection methods. This Thermo Scientific Chemicals brand product was originally part of the Alfa Aesar product portfolio. Some documentation and label information may refer to the legacy brand. The original Alfa Aesar product / item code or SKU reference has not changed as a part of the brand transition to Thermo Scientific Chemicals.

Formula: C₃₂H₅₈N₂O₇S

Color and Shape: Powder, White

Molecular weight: 614.88

Ref: 02-J67359

3-(3-Cholamidopropyl)dimethylammonio-1-propanesulfonate

CAS: 75621-03-3

Formula: C₃₂H₅₈N₂O₇S

Purity: 97%

Color and Shape: Solid

Molecular weight: 614.8771

Ref: IN-DA00ICNA

CHAPS

CAS: 75621-03-3

CHAPS

Purity: ≥98%

Molecular weight: 614.88g/mol

Ref: 54-BUP18782

3-[(3-Cholamidopropyl)dimethylammonio]-1-propanesulphonate Ultrapure

CAS: 75621-03-3

3-[(3-Cholamidopropyl)dimethylammonio]-1-propanesulphonate Ultrapure

Formula: C₃₂H₅₈N₂O₇S

Purity: >99.0%

Color and Shape: white powder

Molecular weight: 614.87712g/mol

Ref: 54-BIMB1085

CHAPS

CAS: 75621-03-3

Formula: C₃₂H₅₈N₂O₇S

Purity: (HPLC) ≥ 98.0%

Color and Shape: White powder

Molecular weight: 614.88

Ref: 7W-GB6883

CHAPS, High Purity

CAS: 75621-03-3

M01449 - CHAPS, High Purity

Formula: C₃₂H₅₈N₂O₇S

Purity: 98%

Color and Shape: Solid, Crystalline Powder or Powder

Molecular weight: 614.88

Ref: 10-M01449

CHAPS

CAS: 75621-03-3

CHAPS is a zwitterionic nondenaturing detergent for solubilizing membrane proteins.

Formula: C₃₂H₅₈N₂O₇S

Purity: 98.2% - 99.75%

Color and Shape: White Crystalline Powder

Molecular weight: 614.88

Ref: TM-T19235

3-[(3-Cholamidopropyl)dimethylammonio]-1-propanesulfonate

Controlled Product

CAS: 75621-03-3

Stability Moisture Sensitive, Hygroscopic
Applications A non-denaturing zwitterionic detergent for membrane biochemistry.
References Hjelmeland, L.H., et al.: Proc. Nat. Acad. Sci. U.S.A., 77, 6368 (1980), Chen, Y., et al.: Biochemistry, 31, 2415 (1992), Ofri, D., et al.: J. Neurochem., 58, 628 (1992),

Formula: C₃₂H₅₈N₂O₇S

Color and Shape: Neat

Molecular weight: 614.88

Ref: TR-C292500

3-((3-Cholamidopropyl)dimethylammonium)-1-propanesulfonate

CAS: 75621-03-3

Non-denaturing, zwitterionic detergent

Formula: C₃₂H₅₈N₂O₇S

Purity: Min. 95%

Color and Shape: White Powder

Molecular weight: 614.88 g/mol

Ref: 3D-FC12196

CHAPS Buffer for molecular biology, 99.5%

CAS: 331717-45-4, 75621-03-3

Formula: C₃₂H₅₈N₂O₇S

Purity: min. 99.5%

Color and Shape: White, Crystalline powder, Clear, Colourless

Molecular weight: 614.89

Ref: SR-21420

CHAPS Buffer extrapure, 99%

CAS: 331717-45-4, 75621-03-3

Formula: C₃₂H₅₈N₂O₇S

Purity: min. 99%

Color and Shape: White, Powder, Clear, Colourless

Molecular weight: 614.89

Ref: SR-87868