CAS 75637-30-8

5-Acetyl-2-(phenylmethoxy)benzamide

Description:

5-Acetyl-2-(phenylmethoxy)benzamide, with the CAS number 75637-30-8, is an organic compound characterized by its structural features, which include an acetyl group and a phenylmethoxy moiety attached to a benzamide framework. This compound typically exhibits a white to off-white crystalline appearance. It is soluble in organic solvents such as ethanol and dimethyl sulfoxide, but may have limited solubility in water due to its hydrophobic characteristics. The presence of the acetyl group suggests potential reactivity, particularly in acylation reactions, while the phenylmethoxy group may influence its electronic properties and interactions with biological targets. The compound may be of interest in medicinal chemistry and drug development, potentially exhibiting biological activity due to its structural components. As with many organic compounds, safety precautions should be observed when handling it, including the use of appropriate personal protective equipment to mitigate any risks associated with exposure.

Formula: C₁₆H₁₅NO₃

InChI: InChI=1S/C16H15NO3/c1-11(18)13-7-8-15(14(9-13)16(17)19)20-10-12-5-3-2-4-6-12/h2-9H,10H2,1H3,(H2,17,19)

InChI key: InChIKey=NTDLDXWJXHCHAA-UHFFFAOYSA-N

SMILES: O(CC1=CC=CC=C1)C2=C(C(N)=O)C=C(C(C)=O)C=C2

Synonyms:

• 5-Acetyl-2-(Benzyloxy)Benzamide
• Benzamide, 5-acetyl-2-(phenylmethoxy)-
• 5-Acetyl-2-(phenylmethoxy)benzamide

5-Acetyl-2-(phenylmethoxy)benzamide

Controlled Product

CAS: 75637-30-8

Applications 5-Acetyl-2-(phenylmethoxy)benzamide is an intermediate of (R,R)-Labetalol (L096500), a specific competitive antagonist at both α-and β-adrenergic receptor sites. (R,R)-Labetalol is used as an antihypertensive.
References Gold, E. H., et al.: J. Med. Chem., 25, 1363 (1982);

Formula: C₁₆H₁₅NO₃

Color and Shape: Neat

Molecular weight: 269.3

Ref: TR-A169475