CAS 756500-23-9

Cyclo(RADfK)

CAS: 756500-23-9

Cyclo(RADfK)

Purity: ≥98%

Molecular weight: 617.7g/mol

Ref: 54-BUP01762

Cyclo(RADfK)

CAS: 756500-23-9

Cyclo(RADfK) is a selective α(v)β(3) integrin ligand used in neoangiogenesis research, therapy, and diagnostics; it's a control for RGD peptides.

Formula: C₂₈H₄₃N₉O₇

Purity: >99.99%

Color and Shape: Solid

Molecular weight: 617.7

Ref: TM-TP1330

Cyclo(Arg-Ala-Asp-D-Phe-Lys)

CAS: 756500-23-9

Cyclo(Arg-Ala-Asp-D-Phe-Lys) is a cyclic peptide that has been shown to have antiangiogenic properties. It may be used as a linker for the conjugation of drugs to compounds with different target specificities. Cyclo(Arg-Ala-Asp-D-Phe-Lys) is a negative control peptide that has the RGD sequence, which is the most common motif in peptides that are used for cell targeting. This peptide was tested against human ovarian carcinoma and inhibited endothelial cell proliferation and tumor vasculature formation. Cyclo(Arg-Ala-Asp-D-Phe-Lys) also inhibited angiogenesis in vitro and in vivo, suggesting that it may be useful for the treatment of cancer and other diseases involving abnormal blood vessel growth.

Formula: C₂₈H₄₃N₉O₇

Purity: Min. 95%

Molecular weight: 617.71 g/mol

Ref: 3D-PCI-3883-PI

Cyclo(-Arg-Ala-Asp-D-Phe-Lys) trifluoroacetate salt

CAS: 756500-23-9

Cyclo(-Arg-Ala-Asp-D-Phe-Lys) trifluoroacetate salt is a peptidomimetic that inhibits the growth of tumor cells by inhibiting angiogenesis, which is the formation of new blood vessels. It has been shown to effectively inhibit the proliferation of endothelial cells and decrease tumor vasculature in human ovarian carcinoma. Cyclo(-Arg-Ala-Asp-D-Phe-Lys) trifluoroacetate salt binds to cyclic peptides in the body and prevents them from being broken down by peptidases. This increases their uptake into cancer cells and inhibits angiogenesis, leading to a decrease in tumor size and number.

Formula: C₂₈H₄₃N₉O₇

Purity: Min. 95%

Molecular weight: 617.7 g/mol

Ref: 3D-FC110055