CAS 75659-08-4

Dilevalol hydrochloride

Description:

Dilevalol hydrochloride is a pharmaceutical compound primarily known for its use as an antihypertensive agent. It is a selective beta-adrenergic blocker that exhibits both beta-1 and beta-2 receptor activity, which helps in managing blood pressure and improving cardiovascular function. The compound is characterized by its ability to induce vasodilation, thereby reducing peripheral resistance and lowering blood pressure. Dilevalol hydrochloride is typically administered in its hydrochloride salt form, which enhances its solubility and bioavailability. The substance is known for its relatively favorable side effect profile compared to non-selective beta-blockers, making it a preferred choice in certain clinical scenarios. Additionally, it may have antioxidant properties, contributing to its therapeutic effects. As with any medication, its use should be guided by a healthcare professional, considering potential interactions and contraindications. Overall, Dilevalol hydrochloride represents a significant option in the management of hypertension and related cardiovascular conditions.

Formula: C₁₉H₂₅ClN₂O₃

InChI: InChI=1/C19H24N2O3.ClH/c1-13(7-8-14-5-3-2-4-6-14)21-12-18(23)15-9-10-17(22)16(11-15)19(20)24;/h2-6,9-11,13,18,21-23H,7-8,12H2,1H3,(H2,20,24);1H/t13-,18+;/m1./s1

InChI key: InChIKey=WQVZLXWQESQGIF-WJKBNZMCSA-N

SMILES: [C@@H](CN[C@@H](CCC1=CC=CC=C1)C)(O)C2=CC(C(N)=O)=C(O)C=C2.Cl

Synonyms:

• (-)-5-((1R)-1-Hydroxy-2-(((1R)-1-methyl-3-phenylpropyl)amino)ethyl)salicylamide monohydrochloride
• (R,R)-5-(1-Hydroxy-2-((1-methyl-3-phenylpropyl)amino)ethyl)salicylamide hydrochloride
• (R,R)-Dilevalol hydrochloride
• (R,R)-Labetalol hydrochloride
• 2-hydroxy-5-[(1R)-1-hydroxy-2-{[(2R)-4-phenylbutan-2-yl]amino}ethyl]benzamide hydrochloride (1:1)
• Benzamide, 2-hydroxy-5-(1-hydroxy-2-((1-methyl-3-phenylpropyl)amino)ethyl)-, monohydrochloride, (R-(R*,R*))-
• Benzamide, 2-hydroxy-5-[(1R)-1-hydroxy-2-[[(1R)-1-methyl-3-phenylpropyl]amino]ethyl]-, hydrochloride (1:1)
• Benzamide, 2-hydroxy-5-[(1R)-1-hydroxy-2-[[(1R)-1-methyl-3-phenylpropyl]amino]ethyl]-, monohydrochloride
• Dilevalol HCl
• Dilevalol hydrochloride
• Dilevalol hydrochloride [USAN:JAN]
• Sch 19927
• Sch 19927 HCl
• Unii-O5Obt75D2C
• Labetalol Hydrochloride Impurity 21（(R,R)-Labetalol Hydrochloride）

(R,R)-Labetalol HCl

CAS: 75659-08-4

Formula: C₁₉H₂₄N₂O₃·HCl

Molecular weight: 328.41 36.36

Ref: 4Z-L-4825

(R,R)-Labetalol Hydrochloride

Controlled Product

CAS: 75659-08-4

Stability Hygroscopic
Applications (R,R)-Labetalol Hydrochloride is a specific competitive antagonist at both α-and β-adrenergic receptor sites. (R,R)-Labetalol Hydrochloride is also used as an antihypertensive.
References Sybertz, E.J., et al.: J. Pharmacol. Exp. Ther., 218, 435 (1981), Clifton, J.E., et al.: J. Med. Chem., 25, 670 (1982), Goa, K.L., et al.: Drugs, 37, 583 (1989),

Formula: C₁₉H₂₄N₂O₃·ClH

Color and Shape: Neat

Molecular weight: 364.87

Ref: TR-L096500

(R,R)-Labetalol-d3 Hydrochloride

Controlled Product

CAS: 75659-07-3, 75659-08-4

Stability Very Hygroscopic
Applications Labelled (R,R)-Labetalol (L096500). (R,R)-Labetalol is a specific competitive antagonist at both α-and β-adrenergic receptor sites. (R,R)-Labetalol is used as an antihypertensive.
References Sybertz, E.J., et al.: J. Pharmacol. Exp. Ther., 218, 435 (1981), Clifton, J.E., et al.: J. Med. Chem., 25, 670 (1982), Goa, K.L., et al.: Drugs, 37, 583 (1989),

Formula: C₁₉H₂₂D₃ClN₂O₃

Color and Shape: Neat

Molecular weight: 367.88

Ref: TR-L096502

Dilevalol hydrochloride

Controlled Product

CAS: 75659-08-4

Beta-adrenoceptor antagonist; anti-hypertensive

Formula: C₁₉H₂₄N₂O₃·HCl

Purity: Min. 95%

Color and Shape: Solid

Molecular weight: 364.87

Ref: 3D-FL24822