CAS 75686-07-6

(13cis)-15-[(4-hydroxyphenyl)amino]retinal

Description:

(13cis)-15-[(4-hydroxyphenyl)amino]retinal, also known by its CAS number 75686-07-6, is a synthetic derivative of retinal, which is a vital chromophore in the visual cycle of vertebrates. This compound features a cis configuration at the 13th carbon position, which influences its interaction with light and its biological activity. The presence of a 4-hydroxyphenylamino group at the 15th position enhances its potential for binding to specific proteins, such as opsins, which are crucial for phototransduction in the retina. The structural modifications impart unique optical properties and may affect its stability and reactivity compared to natural retinal. This compound is of interest in biochemical research, particularly in studies related to vision and photoreceptor function. Its characteristics, including solubility, spectral properties, and reactivity, are influenced by its molecular structure, making it a valuable tool for investigating retinal-related processes and potential therapeutic applications in vision disorders.

Formula: C₂₆H₃₃NO₂

InChI: InChI=1/C26H33NO2/c1-19(11-16-24-21(3)10-7-17-26(24,4)5)8-6-9-20(2)18-25(29)27-22-12-14-23(28)15-13-22/h6,8-9,11-16,18,28H,7,10,17H2,1-5H3,(H,27,29)/b9-6+,16-11+,19-8+,20-18-

Synonyms:

• Retinal, 15-[(4-Hydroxyphenyl)Amino]-, (13Cis)-

13-cis-Fenretinide

Controlled Product

CAS: 75686-07-6

Applications 13-cis-Fenretinide, is an isomer of all-trans-Fenretinide (F250000), which is a synthetic analog of Vitamin A.
References Marth, C., et al.:J. Nat. Cancer Inst., 75, 871 (1985), Delia, D., et al.: Cancer Res., 53, 6036 (1993), Costa., A., et al.: Cancer Res., 54, Suppl., 2032s (1994), Decensi., A., et al.: Eur. J. Cancer Prev., 3, 377 (1994)

Formula: C₂₆H₃₃NO₂

Color and Shape: Neat

Molecular weight: 391.55

Ref: TR-F250005

13-cis-Fenretinide-d4

Controlled Product

CAS: 75686-07-6

Applications 13-cis-Fenretinide-d4, is the labeled analogue of 13-cis-Fenretinide (F250005), which is a synthetic analog of Vitamin A.
References Marth, C., et al.:J. Nat. Cancer Inst., 75, 871 (1985), Delia, D., et al.: Cancer Res., 53, 6036 (1993), Costa., A., et al.: Cancer Res., 54, Suppl., 2032s (1994), Decensi., A., et al.: Eur. J. Cancer Prev., 3, 377 (1994)

Formula: C₂₆D₄H₂₉NO₂

Color and Shape: Neat

Molecular weight: 395.57

Ref: TR-F250007