CymitQuimica logo

CAS 75695-93-1

:

Isradipine

Description:
Isradipine is a dihydropyridine calcium channel blocker primarily used in the treatment of hypertension and angina pectoris. It functions by selectively inhibiting L-type calcium channels, leading to vasodilation and reduced peripheral vascular resistance. Isradipine is characterized by its ability to lower blood pressure without significantly affecting heart rate. The compound is typically administered orally and has a relatively long half-life, allowing for once or twice daily dosing. Its chemical structure includes a dihydropyridine ring, which is essential for its pharmacological activity. Isradipine is known for its favorable side effect profile compared to other antihypertensive agents, although it may still cause peripheral edema, dizziness, or flushing in some patients. The substance is metabolized in the liver, primarily through cytochrome P450 enzymes, and is excreted mainly in the urine. Overall, Isradipine represents an important therapeutic option in cardiovascular medicine, particularly for patients requiring effective blood pressure management.
Formula:C19H21N3O5
InChI:InChI=1/C19H21N3O5/c1-9(2)26-19(24)15-11(4)20-10(3)14(18(23)25-5)16(15)12-7-6-8-13-17(12)22-27-21-13/h6-9,16,20H,1-5H3
InChI key:InChIKey=HMJIYCCIJYRONP-UHFFFAOYSA-N
SMILES:C(OC(C)C)(=O)C=1C(C(C(OC)=O)=C(C)NC1C)C=2C=3C(C=CC2)=NON3
Synonyms:
  • 2,1,3-Benzoxadiazole, 3,5-pyridinedicarboxylic acid deriv.
  • 3,5-Pyridinedicarboxylic acid, 4-(2,1,3-benzoxadiazol-4-yl)-1,4-dihydro-2,6-dimethyl-, 3-methyl 5-(1-methylethyl) ester
  • 3,5-Pyridinedicarboxylic acid, 4-(2,1,3-benzoxadiazol-4-yl)-1,4-dihydro-2,6-dimethyl-, methyl 1-methylethyl ester
  • 3,5-Pyridinedicarboxylic acid, 4-(4-benzofurazanyl)-1,4-dihydro-2,6-dimethyl-, methyl 1-methylethyl ester
  • 3-O-Methyl 5-O-propan-2-yl 4-(2,1,3-benzoxadiazol-4-yl)-2,6-dimethyl-1,4-dihydropyridine-3,5-dicarboxylate
  • Clivoten
  • DynaCirc
  • DynaCirc CR
  • DynaCire
  • DynaCire CR
  • See more synonyms
Sort by
Purity (%)
0
100
|
0
|
50
|
90
|
95
|
100
products per page.Found 21 products.