The chemical substance with the name "(8R,10a'S)-1',1',4,4,12'-pentamethyl-6',7',8',9',10',10a'-hexahydro-1'H,4H,11'H-spiro[1,4-dioxepino[2,3-g]indole-8,2'-[3a,9a](epiminomethano)cyclopenta[b]quinolizine]-9,11'(10H)-dione" and CAS number "75731-43-0" is a complex organic compound characterized by its intricate molecular structure, which includes multiple fused rings and functional groups. This compound features a spirocyclic framework, indicating the presence of a spiro center where two rings share a single atom. The presence of pentamethyl groups suggests a high degree of substitution, which can influence its physical and chemical properties, such as solubility and reactivity. The dioxepin and indole moieties contribute to its potential biological activity, making it of interest in medicinal chemistry. Additionally, the compound's stereochemistry, indicated by the specific configuration at the chiral centers, may play a crucial role in its interaction with biological targets. Overall, this substance exemplifies the complexity often found in natural product derivatives and synthetic organic compounds.

(8R,10a'S)-1',1',4,4,12'-pentamethyl-6',7',8',9',10',10a'-hexahydro-1'H,4H,11'H-spiro[1,4-dioxepino[2,3-g]indole-8,2'-[3a,9a](epiminomethano)cyclopenta[b]quinolizine]-9,11'(10H)-dione

75731-43-0: The chemical substance with the name "(8R,10a'S)-1',1',4,4,12'-pentamethyl-6',7',8',9',10',10a'-hexahydro-1'H,4H,11'H-spiro[1,4-dioxepino[2,3-g]indole-8,2'-[3a,9a](epiminomethano)cyclopenta[b]quinolizine]-9,11'(10H)-dione" and CAS number "75731-43-0" is a complex organic compound characterized by its intricate molecular structure, which includes multiple fused rings and functional groups. This compound features a spirocyclic framework, indicating the presence of a spiro center where two rings share a single atom. The presence of pentamethyl groups suggests a high degree of substitution, which can influence its physical and chemical properties, such as solubility and reactivity. The dioxepin and indole moieties contribute to its potential biological activity, making it of interest in medicinal chemistry. Additionally, the compound's stereochemistry, indicated by the specific configuration at the chiral centers, may play a crucial role in its interaction with biological targets. Overall, this substance exemplifies the complexity often found in natural product derivatives and synthetic organic compounds.

Marcfortine A, an indole alkaloid from P. roqueforti, kills nematodes and inhibits worm motility and human nAChRs.

CAS 75731-43-0

(8R,10a'S)-1',1',4,4,12'-pentamethyl-6',7',8',9',10',10a'-hexahydro-1'H,4H,11'H-spiro[1,4-dioxepino[2,3-g]indole-8,2'-[3a,9a](epiminomethano)cyclopenta[b]quinolizine]-9,11'(10H)-dione

Marcfortine A

Ref: TM-T35745