CAS 75785-12-5
:7-Methyl-5-nitro-1H-indazole
Description:
7-Methyl-5-nitro-1H-indazole is a chemical compound characterized by its indazole core, which is a bicyclic structure containing a five-membered ring fused to a six-membered ring. The presence of a methyl group at the 7-position and a nitro group at the 5-position contributes to its unique chemical properties. This compound is typically a solid at room temperature and may exhibit moderate solubility in organic solvents. It is often used in research and development, particularly in the fields of medicinal chemistry and pharmacology, due to its potential biological activities. The nitro group can participate in various chemical reactions, making it a versatile intermediate in organic synthesis. Additionally, the compound's structure may influence its reactivity, stability, and interaction with biological targets. Safety data should be consulted before handling, as nitro compounds can sometimes be hazardous. Overall, 7-Methyl-5-nitro-1H-indazole serves as an important building block in the synthesis of more complex molecules.
Formula:C8H7N3O2
InChI:InChI=1S/C8H7N3O2/c1-5-2-7(11(12)13)3-6-4-9-10-8(5)6/h2-4H,1H3,(H,9,10)
InChI key:InChIKey=JOJIHKJWRAFXSC-UHFFFAOYSA-N
SMILES:CC1=C2C(=CC(N(=O)=O)=C1)C=NN2
Synonyms:- 1H-Indazole, 7-methyl-5-nitro-
- 7-Methyl-5-nitro-1H-indazole
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Found 4 products.
7-METHYL-5-NITRO-1H-INDAZOLE
CAS:Purity:95.0%Color and Shape:SolidMolecular weight:177.162994384765627-methyl-5-nitro-1H-indazole
CAS:<p>7-Methyl-5-nitro-1H-indazole is an analog of amodiaquine, a drug used in the treatment of malaria. The compound has been shown to be hepatotoxic, which may be due to its metabolic conversion to an amino group. 7-Methyl-5-nitro-1H-indazole inhibits the growth of malaria parasites by causing DNA damage and inhibition of protein synthesis. It is metabolized by hydroxylation and excreted as a stable metabolite. This drug has been shown to be potent against malarial parasites and has anti-malarial properties that are similar to those of amodiaquine.</p>Formula:C8H7N3O2Purity:Min. 95%Molecular weight:177.16 g/mol
