CAS 75790-53-3

dynorphin A fragment 1-8 porcine*sequence

Description:

Dynorphin A fragment 1-8, specifically from porcine sources, is a peptide that consists of eight amino acids derived from the larger dynorphin A molecule, which is an endogenous opioid peptide. This fragment is known for its role in modulating pain, stress responses, and various neurophysiological processes. The sequence of this peptide is characterized by its specific arrangement of amino acids, which contributes to its biological activity, particularly its affinity for opioid receptors, especially the kappa-opioid receptor. Dynorphin A fragment 1-8 exhibits neuroprotective properties and can influence mood and emotional responses. Its CAS number, 75790-53-3, identifies it uniquely in chemical databases, facilitating research and application in pharmacology and neuroscience. Additionally, this peptide is often studied for its potential therapeutic effects in conditions such as addiction, depression, and chronic pain. As a synthetic or naturally derived compound, it is important in understanding the complex interactions of peptides in the central nervous system.

Formula: C₄₆H₇₂N₁₄O₁₀

InChI: InChI=1/C46H72N14O10/c1-5-27(4)38(44(69)70)60-41(66)33(14-10-20-53-46(50)51)57-40(65)32(13-9-19-52-45(48)49)58-42(67)34(21-26(2)3)59-43(68)35(23-28-11-7-6-8-12-28)56-37(63)25-54-36(62)24-55-39(64)31(47)22-29-15-17-30(61)18-16-29/h6-8,11-12,15-18,26-27,31-35,38,61H,5,9-10,13-14,19-25,47H2,1-4H3,(H,54,62)(H,55,64)(H,56,63)(H,57,65)(H,58,67)(H,59,68)(H,60,66)(H,69,70)(H4,48,49,52)(H4,50,51,53)/t27-,31-,32-,33?,34-,35-,38-/m0/s1

SMILES: CC[C@H](C)[C@@H](C(=O)O)N=C(C(CCCNC(=N)N)N=C([C@H](CCCNC(=N)N)N=C([C@H](CC(C)C)N=C([C@H](Cc1ccccc1)N=C(CN=C(CN=C([C@H](Cc1ccc(cc1)O)N)O)O)O)O)O)O)O

Synonyms:

• Dynorphin A (1-8)
• H-Tyr-Gly-Gly-Phe-Leu-Arg-Arg-Ile-OH
• L-tyrosylglycylglycyl-L-phenylalanyl-L-leucyl-N~5~-(diaminomethylidene)-L-ornithyl-N~5~-(diaminomethylidene)ornithyl-L-isoleucine

Dynorphin A (1-8)

CAS: 75790-53-3

Bachem ID: 4005845.

Formula: C₄₆H₇₂N₁₄O₁₀

Purity: > 99%

Color and Shape: White Lyophilisate

Molecular weight: 981.17

Ref: 01-4005845

Dynorphin A (1-8)

CAS: 75790-53-3

Dynorphin (1-8) is an opioid octapeptide from the porcine hypothalamus. It comprises the N-terminal eight residues of dynorphin.

Formula: C₄₆H₇₂N₁₄O₁₀

Purity: 98%

Color and Shape: Solid

Molecular weight: 981.15

Ref: TM-T20403

Dynorphin A (1-8)

CAS: 75790-53-3

Custom research peptide; min purity 95%. For different specs please use the Peptide Quote Tool

Formula: C₄₆H₇₂N₁₄O₁₀

Molecular weight: 981.17 g/mol

Ref: 3D-PP50355

Dynorphin A (1-8) acetate salt

CAS: 75790-53-3

Dynorphin A (1-8) acetate salt H-Tyr-Gly-Gly-Phe-Leu-Arg-Arg-Ile-OH acetate salt is a synthetic, nonpeptide opioid agonist. It binds to the delta receptor and inhibits nociception in the central nervous system. This compound has been shown to produce acute phase and subchronic toxicity in rats and has been shown to possess antinociceptive effects in mice. Dynorphin A (1-8) acetate salt H-Tyr-Gly-Gly-Phe-Leu-Arg-Arg-Ile-OH acetate salt has also been shown to antagonize the enzyme inhibitors of phospholipase A2, cyclooxygenase, and lipoxygenase.
MECHANISM OF ACTION: Dynorphin A (1–8) is an endogenous peptide that modulates neurotransmission at the

Formula: C₄₆H₇₂N₁₄O₁₀

Purity: Min. 95%

Molecular weight: 981.15 g/mol

Ref: 3D-FD108731