CAS 75871-31-7

β-D-Glucopyranuronic acid, 1-[5-(4-chlorobenzoyl)-1,4-dimethyl-1H-pyrrole-2-acetate]

Description:

β-D-Glucopyranuronic acid, 1-[5-(4-chlorobenzoyl)-1,4-dimethyl-1H-pyrrole-2-acetate] is a complex organic compound characterized by its structural features, which include a glucopyranuronic acid moiety and a pyrrole derivative with a chlorobenzoyl substituent. The glucopyranuronic acid component contributes to its potential biological activity, as uronic acids are often involved in polysaccharide structures and can play roles in cellular processes. The presence of the 4-chlorobenzoyl group enhances the compound's lipophilicity, potentially influencing its interaction with biological membranes and receptors. The dimethyl substitution on the pyrrole ring may affect the compound's electronic properties and reactivity. This compound is likely to exhibit solubility in polar solvents due to the hydroxyl groups in the glucopyranuronic acid, while the aromatic and halogenated components may provide additional interactions in organic solvents. Overall, the unique combination of functional groups suggests potential applications in pharmaceuticals or biochemistry, although specific biological activities would require further investigation.

Formula: C₂₁H₂₂ClNO₉

InChI: InChI=1S/C21H22ClNO9/c1-9-7-12(23(2)14(9)15(25)10-3-5-11(22)6-4-10)8-13(24)31-21-18(28)16(26)17(27)19(32-21)20(29)30/h3-7,16-19,21,26-28H,8H2,1-2H3,(H,29,30)/t16-,17-,18+,19-,21+/m0/s1

InChI key: InChIKey=FNGKIZYZSHHXJZ-ZFORQUDYSA-N

SMILES: C(=O)(C=1N(C)C(CC(O[C@@H]2O[C@H](C(O)=O)[C@@H](O)[C@H](O)[C@H]2O)=O)=CC1C)C3=CC=C(Cl)C=C3

Synonyms:

• β-D-Glucopyranuronic acid, 1-[5-(4-chlorobenzoyl)-1,4-dimethyl-1H-pyrrole-2-acetate]
• Zomepirac glucuronide

Zomepirac acyl-β-D-glucuronide

CAS: 75871-31-7

Ref: 7W-GC7379

Zomepirac-acyl-β-D-Glucuronide

CAS: 75871-31-7

Formula: C₂₁H₂₂ClNO₉

Molecular weight: 467.86

Ref: 4Z-Z-024001

Zomepirac-acyl-β-D-glucuronide

CAS: 75871-31-7

Zomepirac-acyl-β-D-glucuronide

Purity: >97%

Color and Shape: Solid

Molecular weight: 467.85g/mol

Ref: 54-BICL4221

Zomepirac Acyl-O-β-D-glucuronide

Controlled Product

CAS: 75871-31-7

Stability Hygroscopic
Applications An unstable metabolite of the nonsteroidal anti-inflammatory drug (NSAID) Zomepirac (Z675000) that is capable of reacting with endogenous proteins to form potentially toxic covalent ZP-protein adducts.
Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package
References King, A.R. et al.: J. Phamacol. Toxicol. Meth., 36, 131 (1996); Olsen, J. et al.: Chem. Res. Toxicol., 18, 1729 (2005); O’Neill, P.J. et al.: J. Clin. Pharmacol., 22, 470 (1982);

Formula: C₂₁H₂₂ClNO₉

Color and Shape: Beige

Molecular weight: 467.85

Ref: TR-Z675010

Zomepirac-acyl-b-D-glucuronide

CAS: 75871-31-7

Zomepirac-acyl-b-D-glucuronide is a metabolite of the nonsteroidal anti-inflammatory drug zomepirac. It binds to plasma proteins, which may affect its pharmacokinetics. Zomepirac-acyl-b-D-glucuronide is excreted in the urine and may be bound to fatty acids. The drug has been shown to form covalent adducts with lysine residues in humans, which may result in potential interactions with other drugs or increased toxicity. The drug has been studied in clinical pharmacology studies that show no significant adverse effects in humans. This metabolite has also been shown to have fatty acid binding properties, which may affect its pharmacokinetics and metabolism.

Formula: C₂₁H₂₂ClNO₉

Purity: Min. 95%

Color and Shape: Powder

Molecular weight: 467.85 g/mol

Ref: 3D-MZ44758