CAS 75887-54-6

Arteether

Description:

Arteether, with the CAS number 75887-54-6, is an antimalarial compound derived from artemisinin, which is extracted from the sweet wormwood plant, Artemisia annua. It is classified as an ether derivative and is primarily used in the treatment of severe malaria, particularly in cases where resistance to other antimalarial drugs is observed. Arteether exhibits a rapid onset of action and is effective against Plasmodium falciparum, the most virulent malaria parasite. The compound is typically administered via intramuscular injection, which allows for quick absorption and distribution in the body. Arteether works by generating reactive oxygen species that damage the parasite's cellular components, leading to its death. Its pharmacokinetics involve a relatively short half-life, necessitating careful dosing and monitoring. Arteether is generally well-tolerated, but like all medications, it may have side effects, including potential neurotoxicity and allergic reactions. Overall, it plays a crucial role in malaria treatment protocols, especially in regions with high rates of drug-resistant malaria.

Formula: C₁₇H₂₈O₅

InChI: InChI=1S/C17H28O5/c1-5-18-14-11(3)13-7-6-10(2)12-8-9-16(4)20-15(19-14)17(12,13)22-21-16/h10-15H,5-9H2,1-4H3/t10-,11-,12+,13+,14+,15-,16-,17-/m1/s1

InChI key: InChIKey=NLYNIRQVMRLPIQ-XQLAAWPRSA-N

SMILES: C[C@@H]1[C@]2([C@]34[C@](O[C@@H]1OCC)(O[C@](C)(OO3)CC[C@]4([C@H](C)CC2)[H])[H])[H]

Synonyms:

• (3R,5aS,6R,8aS,9R,10S,12R,12aR)-10-Ethoxydecahydro-3,6,9-trimethyl-3,12-epoxy-12H-pyrano[4,3-j]-1,2-benzodioxepin
• (3R,5aS,6R,8aS,9R,12R,12aR)-10-ethoxy-3,6,9-trimethyldecahydro-3,12-epoxy[1,2]dioxepino[4,3-i]isochromene
• (5aS,6R,8aS,9R,10S,12R,12aR)-10-ethoxy-3,6,9-trimethyldecahydro-3,12-epoxy[1,2]dioxepino[4,3-i]isochromene
• 10-Ethoxy-3,6,9-Trimethyldecahydro-3,12-Epoxy[1,2]Dioxepino[4,3-I]Isochromene
• 10-Ethoxydecahydro-3,6,9-trimethyl-3,12-epoxy-12H-pyrano(4,3-j)-1,2-benzodioxepin
• 3,12-Epoxy-12H-pyrano(4,3-j)-1,2-benzodioxepin, 10-ethoxydecahydro-3,6,9-trimethyl-
• 3,12-Epoxy-12H-pyrano[4,3-j]-1,2-benzodioxepin, 10-ethoxydecahydro-3,6,9-trimethyl-, (3R,5aS,6R,8aS,9R,10S,12R,12aR)-
• 3,12-Epoxy-12H-pyrano[4,3-j]-1,2-benzodioxepin, 10-ethoxydecahydro-3,6,9-trimethyl-, [3R-(3α,5aβ,6β,8aβ,9α,10α,12β,12aR*)]-
• Artemotil
• Dihydroartemisinin ethyl ether
• Dihydroqinghaosu ethyl ether
• NSC 665971
• Sm 227
• beta-Artether
• β-Arteether
• β-Dihydroartemisinin ethyl ether

Arteether

CAS: 75887-54-6

Formula: C₁₇H₂₈O₅

Purity: 98%

Color and Shape: Solid

Molecular weight: 312.4012

Ref: IN-DA008P4I

Artemotil

CAS: 75887-54-6

Artemotil

Purity: ≥98%

Molecular weight: 312.4g/mol

Ref: 54-BUP00050

Arteether

CAS: 75887-54-6

Arteether

Purity: 98%

Molecular weight: 312.4g/mol

Ref: 54-OR1026448

Arteether

CAS: 75887-54-6

Formula: C₁₇H₂₈O₅

Molecular weight: 312.41

Ref: 4Z-A-131001

Arteether

CAS: 75887-54-6

Formula: C₁₇H₂₈O₅

Molecular weight: 312.41

Ref: 7W-GY1618

Arteether

CAS: 75887-54-6

Formula: C₁₇H₂₈O₅

Purity: 95%~99%

Molecular weight: 312.406

Ref: BP-BP4357

Artemotil

CAS: 75887-54-6

Artemotil (SM-227) is a new, fast-acting antimalarial drug.

Formula: C₁₇H₂₈O₅

Purity: 99.76% - 99.88%

Color and Shape: White Crystalline Solid

Molecular weight: 312.4

Ref: TM-T3327