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CAS 75898-90-7

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Amrinone lactate

Description:
Amrinone lactate, with the CAS number 75898-90-7, is a pharmaceutical compound primarily used as a cardiotonic agent. It is a derivative of amrinone, which is known for its ability to enhance cardiac contractility and improve hemodynamic parameters in patients with heart failure. The lactate form of amrinone is often utilized for its solubility and stability in intravenous formulations. Characteristically, amrinone lactate functions as a phosphodiesterase inhibitor, leading to increased levels of cyclic AMP in cardiac tissues, which subsequently enhances myocardial contractility and promotes vasodilation. This compound is typically administered in a clinical setting under careful monitoring due to potential side effects, including arrhythmias and hypotension. Its pharmacokinetics involve rapid absorption and distribution, with metabolism primarily occurring in the liver. Overall, amrinone lactate plays a significant role in the management of acute heart failure, providing symptomatic relief and improving cardiac output in critically ill patients.
Formula:C10H9N3O·xC3H6O3
InChI:InChI=1S/C10H9N3O.C3H6O3/c11-9-5-8(6-13-10(9)14)7-1-3-12-4-2-7;1-2(4)3(5)6/h1-6H,11H2,(H,13,14);2,4H,1H3,(H,5,6)
InChI key:InChIKey=DOSIONJFGDSKCQ-UHFFFAOYSA-N
SMILES:NC1=CC(=CNC1=O)C=2C=CN=CC2.C(C(O)=O)(C)O
Synonyms:
  • Propanoic acid, 2-hydroxy-, compd. with 5-amino[3,4′-bipyridin]-6(1H)-one
  • Propanoic acid, 2-hydroxy-, compd. with 5-amino[3,4′-bipyridin]-6(1H)-one (1:?)
  • Inocor
  • [3,4′-Bipyridin]-6(1H)-one, 5-amino-, 2-hydroxypropanoate
  • Amrinone lactate
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