CAS 75899-68-2

4-Hydroxynonenal

Description:

4-Hydroxynonenal (4-HNE) is a reactive aldehyde and a product of lipid peroxidation, primarily derived from the degradation of omega-6 fatty acids. It is characterized by its unsaturated carbon chain, containing a hydroxyl group and an aldehyde functional group, which contribute to its reactivity and biological significance. 4-HNE is known for its role as a signaling molecule and is involved in various cellular processes, including apoptosis, inflammation, and oxidative stress responses. Its reactivity allows it to form adducts with proteins, DNA, and lipids, potentially leading to cellular damage and contributing to the pathophysiology of several diseases, including neurodegenerative disorders and cancer. Additionally, 4-HNE exhibits antioxidant properties, which can help mitigate oxidative damage under certain conditions. Due to its dual role as both a signaling molecule and a potential toxicant, 4-HNE is of significant interest in research related to oxidative stress and its implications in health and disease.

Formula: C₉H₁₆O₂

InChI: InChI=1/C9H16O2/c1-2-3-4-6-9(11)7-5-8-10/h5,7-9,11H,2-4,6H2,1H3/b7-5+

InChI key: InChIKey=JVJFIQYAHPMBBX-FNORWQNLNA-N

SMILES: C(C(/C=C/C=O)O)CCCC

Synonyms:

• (2E)-4-Hydroxy-2-nonenal
• (E)-4-Hydroxy-2-nonenal
• 4-Hydroxy-2(E)-nonenal
• 4-Hydroxy-2-nonenal
• 4-Hydroxy-2-trans-nonenal
• 4-Hydroxynonenal
• Nonenal, 4-hydroxy-
• 2-Nonenal, 4-hydroxy-, (2E)-

4-hydroxy Nonenal

CAS: 75899-68-2

Formula: C₉H₁₆O₂

Purity: 97%

Color and Shape: Liquid

Molecular weight: 156.2221

Ref: IN-DA000YP4

4-Hydroxynonenal

CAS: 75899-68-2

4-Hydroxynonenal (4-HNE) (4-HNE) is an oxidative/nitrosative stress biomarker. It is a substrate and an inhibitor of acetaldehyde dehydrogenase 2 (ALDH2).

Formula: C₉H₁₆O₂

Purity: 95.12% - 98%

Color and Shape: Clear Colorless Liquid

Molecular weight: 156.22

Ref: TM-T10148

4-Hydroxy-2-Nonenal

CAS: 75899-68-2

Formula: C₉H₁₆O₂

Molecular weight: 156.23

Ref: 4Z-F-106178

4-Hydroxynonenal

CAS: 75899-68-2

4-Hydroxynonenal

Purity: ≥95%

Molecular weight: 156.22g/mol

Ref: 54-BUP03658

4-hydroxy-2(E)-nonenal

CAS: 75899-68-2

Formula: C9H16O2

Purity: >98%

Color and Shape: In solution, Ethanol

Molecular weight: 156.22

Ref: 48-12-0902

(E)-4-HYDROXY-2-NONENAL

CAS: 75899-68-2

Purity: 97%

Molecular weight: 156.2250061

Ref: 10-F835915

4-Hydroxynonenal

Controlled Product

CAS: 75899-68-2

Applications 4-Hydroxynonenal is an irreversible inhibitor of Na+/K+-ATPase activity.

Formula: C₉H₁₆O₂

Color and Shape: Neat

Molecular weight: 156.222

Ref: TR-H948793