Dynorphin A D-arg6-fragment 1-13, also known by its CAS number 75921-87-8, is a peptide that is part of the dynorphin family, which are endogenous opioid peptides derived from proenkephalin. This specific fragment consists of 13 amino acids and is characterized by its role in modulating pain, stress responses, and emotional behaviors through its interaction with opioid receptors, particularly the kappa-opioid receptor. The D-arginine substitution at position 6 enhances its stability and bioactivity compared to its natural counterparts. Dynorphin A fragments are known for their neuropeptide functions, influencing neurotransmission and exhibiting potential neuroprotective effects. The porcine sequence indicates that this peptide is derived from porcine sources, which may have implications for its biological activity and therapeutic applications. Overall, dynorphin A D-arg6-fragment 1-13 is significant in research related to pain management, addiction, and mood disorders, making it a subject of interest in pharmacological studies.

dynorphin A D-arg6-fragment 1-13*porcine sequence

75921-87-8: Dynorphin A D-arg6-fragment 1-13, also known by its CAS number 75921-87-8, is a peptide that is part of the dynorphin family, which are endogenous opioid peptides derived from proenkephalin. This specific fragment consists of 13 amino acids and is characterized by its role in modulating pain, stress responses, and emotional behaviors through its interaction with opioid receptors, particularly the kappa-opioid receptor. The D-arginine substitution at position 6 enhances its stability and bioactivity compared to its natural counterparts. Dynorphin A fragments are known for their neuropeptide functions, influencing neurotransmission and exhibiting potential neuroprotective effects. The porcine sequence indicates that this peptide is derived from porcine sources, which may have implications for its biological activity and therapeutic applications. Overall, dynorphin A D-arg6-fragment 1-13 is significant in research related to pain management, addiction, and mood disorders, making it a subject of interest in pharmacological studies.

<p>Dynorphin A (1-13) H-Tyr-Gly-Gly-Phe-Leu <br>Dynorphin A (1-13) H-Tyr-Gly-Gly-Phe is a synthetic substrate for κ opioid receptors. It also has antinociceptive properties and may be used as a potential analgesic drug. Dynorphin A (1-13) H-Tyr-Gly-Gly <br>Dynorphin A (1-13) H Tyr Gly Gly Phe Leu D Arg Arg Arg Ile Arg Pro Lys Leu Lys OH has been shown to be effective in the treatment of humans and rats with cardiac or physiological function problems. Dynorphin A (1 13) H Tyr Gly Gly Phe Leu D Arg Arg Arg Ile Arg Pro Lys Leu Lys OH increases serum prolactin levels in humans, which may indicate that it stimulates the hypothalamus to</p>

CAS 75921-87-8

dynorphin A D-arg6-fragment 1-13*porcine sequence

(D-Arg6)-Dynorphin A (1-13)

Ref: 3D-FA108726