CAS 75970-64-8

1H-Benzimidazol-2-amine, 1-[(4-fluorophenyl)methyl]-N-4-piperidinyl-, hydrobromide (1:2)

Description:

1H-Benzimidazol-2-amine, 1-[(4-fluorophenyl)methyl]-N-4-piperidinyl-, hydrobromide (1:2) is a chemical compound characterized by its complex structure, which includes a benzimidazole core, a piperidine moiety, and a fluorophenyl group. This compound typically appears as a crystalline solid and is soluble in polar solvents, reflecting its ionic hydrobromide form. The presence of the piperidine ring contributes to its potential biological activity, often associated with pharmacological properties. The fluorophenyl substituent may enhance lipophilicity and influence the compound's interaction with biological targets. As a hydrobromide salt, it is often more stable and easier to handle than its free base form. This compound is of interest in medicinal chemistry, particularly for its potential applications in drug development, where modifications to the benzimidazole structure can lead to varied biological activities. Safety and handling precautions should be observed, as with all chemical substances, due to potential toxicity and reactivity.

Formula: C₁₉H₂₁FN₄·2BrH

InChI: InChI=1S/C19H21FN4.2BrH/c20-15-7-5-14(6-8-15)13-24-18-4-2-1-3-17(18)23-19(24)22-16-9-11-21-12-10-16;;/h1-8,16,21H,9-13H2,(H,22,23);2*1H

InChI key: InChIKey=IVXYTQSEWOVUDL-UHFFFAOYSA-N

SMILES: C(N1C=2C(N=C1NC3CCNCC3)=CC=CC2)C4=CC=C(F)C=C4.Br

Synonyms:

• 1H-Benzimidazol-2-amine, 1-[(4-fluorophenyl)methyl]-N-4-piperidinyl-, hydrobromide (1:2)
• 1-(4-Fluorobenzyl)-N-piperidin-4-yl-1H-benzimidazol-2-amine dihydrobromide
• Norastemizole hydrobromide
• 1H-Benzimidazol-2-amine, 1-[(4-fluorophenyl)methyl]-N-4-piperidinyl-, dihydrobromide
• R 41232

Norastemizole Hydrobromide

Controlled Product

CAS: 75970-64-8

Applications An antihistamine used to treat allergic rhinitis and asthma which does not induce adverse effects such as cardiac arrhythmia, fatigue, or general body weakness.
References Janssens, F., et al.: J. Med. Chem., 28, 1934 (1985),

Formula: C₁₉H₂₃Br₂FN₄

Color and Shape: Neat

Molecular weight: 486.22

Ref: TR-N661060