CAS 76-75-5

(±)-Thiopental

Description:

(±)-Thiopental, with the CAS number 76-75-5, is a barbiturate anesthetic known for its rapid onset and short duration of action. It appears as a white crystalline powder that is soluble in water and has a slightly bitter taste. This compound is primarily used in medical settings for induction of anesthesia and as a sedative. Its mechanism of action involves enhancing the inhibitory neurotransmitter gamma-aminobutyric acid (GABA) at the GABA-A receptor, leading to CNS depression. (±)-Thiopental is classified as a controlled substance due to its potential for abuse and dependence. The drug is typically administered intravenously, and its effects can be influenced by factors such as dosage, patient metabolism, and concurrent medications. Side effects may include respiratory depression, hypotension, and allergic reactions. Due to its rapid metabolism and clearance, it is often favored for short surgical procedures. However, its use has declined in favor of newer anesthetics with improved safety profiles and fewer side effects.

Formula:C₁₁H₁₈N₂O₂S

InChI:InChI=1/C11H18N2O2S/c1-4-6-7(3)11(5-2)8(14)12-10(16)13-9(11)15/h7H,4-6H2,1-3H3,(H2,12,13,14,15,16)

InChI key:InChIKey=IUJDSEJGGMCXSG-UHFFFAOYSA-N

SMILES:C(CCC)(C)C1(CC)C(=O)NC(=S)NC1=O

Synonyms:

(.+-.)-Thiopental
2-Thio-5-ethyl-5-sec-pentylbarbituric acid
5-Ethyl-5-(1-Methylbutyl)-2-Thiobarbituric Acid
5-Ethyl-5-(1-methylbutyl)-2-thiobarbiturate
5-Ethyl-5-(1-methylbutyl)-2-thiobarbitursaure
5-Ethyldihydro-5-(1-methylbutyl)-2-thioxo-4,6(1H,5H)-pyrimidinedione
Acide 5-Ethyl-5-(1-Methylbutyl)-2-Thiobarbiturique
Acido 5-Etil-5-(1-Metilbutil)-2-Tiobarbiturico
Barbituric acid, 5-ethyl-5-(1-methylbutyl)-2-thio-
Intraval
Penthiobarbital
Pentothiobarbital
Thiomebumal
Thionembutal
Thiopentobarbital
Thiopentobarbitone
Thiopentobarbituric acid
Thiopentone
Thiothal
4,6(1H,5H)-Pyrimidinedione, 5-ethyldihydro-5-(1-methylbutyl)-2-thioxo-
Sodium thiopental
sodium 5-ethyl-5-(1-methylbutyl)-6-oxo-2-thioxo-1,2,5,6-tetrahydropyrimidin-4-olate
5-ethyl-5-(1-methylbutyl)-2-thioxodihydropyrimidine-4,6(1H,5H)-dione
(+-)-thiopental methanol solution
Barbituric acid, 5-ethyl-5-(1-methylbutyl)-2-thio- (8CI)
5-Ethyl-5-(1-methylbutyl)-2-thiobarbitirobic acid
Pentothal
5-ethyl-5-pentan-2-yl-2-sulfanylidene-1,3-diazinane-4,6-dione
5-ETHYL-5-PENTAN-2-YL-2-SULFANYL-1H-PYRIMIDINE-4,6-DIONE
5-Ethyl-5-(1-methylbutyl)-2-thioxodihydro-4,6(1H,5H)-pyrimidinedione
Thiopental for system suitability
Thiopental CIII (250 mg)
Nesdonal
(+,-)-thiopental free acid--dea*schedule iii item
4,6(1H,5H)-Pyrimidinedione, 5-ethyldihydro-5-(1-methylbutyl)-2-thioxo- (9CI)
5-Ethyl-5-[(S)-1-methylbutyl]-2-thioxo-1,2-dihydropyrimidine-4,6(3H,5H)-dione
Thiopental CRS
Thiopental for system suitability CRS
PENTOTHAL ACID
5-ethyl-5-(1-methylbutyl)-2-thio-barbituricaci
(1h,5h)-pyrimidinedione,5-ethyldihydro-5-(1-methylbutyl)-2-thioxo-6
(±)thiopental solution
Thiopental for system suitability (Y0001478)
See more synonyms

The purity filter is not visible because current products do not have associated purity data for filtering.

Found 7 products.

+ Info
Thiopental
Controlled ProductPlease note that this is a controlled product in some countries, and needs to be treated in accordance with the relevant regulations. Be aware this might entail additional expenses and documentation.
CAS:
- 76-75-5
Color and Shape:Neat
Ref: LP-TPT-1099-FA-10
10mg
93.00€
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50mg
204.00€
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100mg
333.00€
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Thiopental
Controlled ProductPlease note that this is a controlled product in some countries, and needs to be treated in accordance with the relevant regulations. Be aware this might entail additional expenses and documentation.
CAS:
- 76-75-5
Color and Shape:Neat
Ref: 61-FOR1312.06
5mg
352.00€
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Thiopental, 1mg/ml in Methanol
Controlled ProductPlease note that this is a controlled product in some countries, and needs to be treated in accordance with the relevant regulations. Be aware this might entail additional expenses and documentation.
CAS:
- 76-75-5
Color and Shape:Single Solution
Ref: LP-TPT-1099-FA-1LM
1ml
65.00€
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THIOPENTAL FOR ID AND ASSAY CRS
CAS:
- 76-75-5
THIOPENTAL FOR ID AND ASSAY CRS
Ref: 41-Y0002374
500mg
167.00€
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Thiopental
Controlled ProductPlease note that this is a controlled product in some countries, and needs to be treated in accordance with the relevant regulations. Be aware this might entail additional expenses and documentation.
CAS:
- 76-75-5
Applications A thio-derivative of Barbituric acid. Controlled substance (depressant). Anesthetic. GABAA receptor agonist acting as a positive allosteric modulator. Neuroprotective & Neuroresearch Products.
Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package
References Christensen, L., et al.: Toxicol. Appl. Pharmacol., 26, 495 (1973), McLeish, M. J., Anal. Profiles Drug Subs. Excip., 21, 535 (1992),
Formula:C₁₁H₁₈N₂O₂S
Color and Shape:White To Cream-Coloured
Molecular weight:242.34
Ref: TR-T344800
10mg
103.00€
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100mg
144.00€
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250mg
246.00€
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Thiopental (1 mg/ml in Acetonitrile)
Controlled ProductPlease note that this is a controlled product in some countries, and needs to be treated in accordance with the relevant regulations. Be aware this might entail additional expenses and documentation.
CAS:
- 76-75-5
Formula:C₁₁H₁₈N₂O₂S
Color and Shape:Single Solution
Molecular weight:242.34
Ref: TR-KIT7490
10x1ml
210.00€
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Thiopental CIII
Controlled ProductPlease note that this is a controlled product in some countries, and needs to be treated in accordance with the relevant regulations. Be aware this might entail additional expenses and documentation.
CAS:
- 76-75-5
Drugs containing a pyrimidine ring (whether or not hydr
Formula:C₁₁H₁₈N₂O₂S
Color and Shape:Powder
Molecular weight:242.1089
Ref: 45-1661002