CAS 76-96-0
:Methiotepa
Description:
Methiotepa, with the CAS number 76-96-0, is a chemical compound classified as an antineoplastic agent, primarily used in cancer treatment. It is a member of the alkylating agents, which function by interfering with the DNA replication process, thereby inhibiting the growth of cancer cells. Methiotepa is characterized by its ability to form covalent bonds with DNA, leading to cross-linking and subsequent cell death. The compound is typically administered in a clinical setting and may be used in combination with other chemotherapy agents to enhance therapeutic efficacy. Its pharmacokinetics involve metabolism in the liver, and it is excreted primarily through the kidneys. Side effects can include myelosuppression, gastrointestinal disturbances, and potential toxicity to other organs. Due to its potent effects, Methiotepa is handled with caution, and its use is generally restricted to specialized medical environments where patient monitoring can be conducted. As with all chemotherapeutic agents, the benefits must be weighed against the risks, and treatment regimens are tailored to individual patient needs.
Formula:C9H18N3PS
InChI:InChI=1/C9H18N3PS/c1-7-4-10(7)13(14,11-5-8(11)2)12-6-9(12)3/h7-9H,4-6H2,1-3H3
InChI key:InChIKey=MLFGIRNMAOXTHS-UHFFFAOYSA-N
SMILES:P(=S)(N1C(C)C1)(N2C(C)C2)N3C(C)C3
Synonyms:- 1,1′,1′′-Phosphinothioylidynetris[2-methylaziridine]
- Ai3-50004
- Aziridine, 1,1',1''-phosphinothioylidynetris(2-methyl- (9CI)
- Aziridine, 1,1′,1′′-phosphinothioylidynetris[2-methyl-
- Ent 161A
- Ent 50782
- Maps
- Metapside
- Methiotepa
- NSC 56843
- Nsc 54055
- Phosphine sulfide, tris(2-methyl-1-aziridinyl)-
- Phosphine sulfide, tris(2-methyl-1-aziridinyl)- (8CI)
- Tris(2-methyl-1-aziridinyl)phosphine sulfide
- 1,1',1''-Phosphorothioyltris(2-methylaziridine)
- tris(2-methylaziridin-1-yl)-sulfanylidene-$l^{5}-phosphane
- See more synonyms
Sort by
Purity (%)
0
100
|
0
|
50
|
90
|
95
|
100
Found 2 products.
Methiotepa
CAS:<p>Methiotepa is a potent anticancer drug that has been used for the treatment of various types of tumors. It is a Chinese hamster ovary (CHO) cell-derived analog of chitin, which inhibits the activity of protein kinase C. Methiotepa induces apoptosis in cancer cells by inhibiting DNA synthesis and repair, leading to cell death. This drug has also been shown to be a potent inhibitor of heparin-induced platelet aggregation in human blood. Methiotepa has been found to be effective against a wide range of cancers, including breast, lung, ovarian, and bladder cancer, among others. Its use as an anticancer agent may be due to its ability to inhibit the activity of various kinases and other enzymes involved in cancer cell proliferation and survival.</p>Formula:C9H18N3PSPurity:Min. 95%Molecular weight:231.3 g/mol
