CAS 76003-29-7

1-Boc-3-oxopiperazine

Description:

1-Boc-3-oxopiperazine, with the CAS number 76003-29-7, is a chemical compound characterized by its piperazine core, which is a six-membered heterocyclic ring containing two nitrogen atoms. The "Boc" (tert-butyloxycarbonyl) group is a common protecting group used in organic synthesis, particularly in peptide chemistry, to temporarily mask amine functionalities. The presence of the oxo group indicates that there is a carbonyl (C=O) functionality at the 3-position of the piperazine ring, contributing to its reactivity and potential applications in various chemical reactions. This compound is typically used as an intermediate in the synthesis of pharmaceuticals and other biologically active molecules. Its properties, such as solubility and stability, can be influenced by the presence of the Boc group and the oxo functionality, making it a versatile building block in organic synthesis. As with many chemical substances, handling should be done with care, following appropriate safety protocols due to potential hazards associated with its reactivity and toxicity.

Formula: C₉H₁₆N₂O₃

InChI: InChI=1/C9H16N2O3/c1-9(2,3)14-8(13)11-5-4-10-7(12)6-11/h4-6H2,1-3H3,(H,10,12)

SMILES: CC(C)(C)OC(=O)N1CCN=C(C1)O

Synonyms:

• Tert-butyl-3-oxo-1-piperazinecarboxylate
• Tert-Butyl 3-Oxopiperazine-1-Carboxylate
• 3-Oxo-Piperazine-1-Carboxylic Acid Tert-Butyl Ester

tert-Butyl 3-Oxopiperazine-1-carboxylate

CAS: 76003-29-7

Formula: C₉H₁₆N₂O₃

Purity: >98.0%(GC)

Color and Shape: White to Yellow to Orange powder to crystal

Molecular weight: 200.24

Ref: 3B-B3804

1-Boc-3-oxopiperazine, 98%

CAS: 76003-29-7

This Thermo Scientific Chemicals brand product was originally part of the Alfa Aesar product portfolio. Some documentation and label information may refer to the legacy brand. The original Alfa Aesar product / item code or SKU reference has not changed as a part of the brand transition to Thermo Sci

Formula: C₉H₁₆N₂O₃

Purity: 98%

Color and Shape: Crystals or powder or crystalline powder, White to pale cream or pale yellow

Molecular weight: 200.24

Ref: 02-H27823

1-Boc-3-oxopiperazine

CAS: 76003-29-7

Formula: C₉H₁₆N₂O₃

Purity: 97%

Color and Shape: Solid

Molecular weight: 200.2349

Ref: IN-DA003E1C

Piperazin-3-one, N1-BOC protected

CAS: 76003-29-7

Piperazin-3-one, N1-BOC protected

Formula: C₉H₁₆N₂O₃

Purity: ≥95%

Color and Shape: solid

Molecular weight: 200.23g/mol

Ref: 54-OR4569

4-N-Boc-2-Oxo-piperazine

CAS: 76003-29-7

Formula: C₉H₁₆N₂O₃

Purity: 97%

Color and Shape: Solid, Off-white solid

Molecular weight: 200.238

Ref: 10-F040522

4-Boc-2-oxopiperazine

Controlled Product

CAS: 76003-29-7

Applications 4-Boc-2-oxopiperazine is used in the synthesis of renin inhibitors. Also used in the synthesis of isoindoline inhibitors of dipeptidyl peptidases.
References Nakamura, Y. et al.: Bioorg. Med. Chem. Lett., 22, 4561 (2012); Van G. et al.: J. Med. Chem., 54, 5737 (2011);

Formula: C₉H₁₆N₂O₃

Color and Shape: Neat

Molecular weight: 200.23

Ref: TR-B658935