CAS 76034-18-9

(8S,10S)-10-[(3-Amino-2,3,6-trideoxy-α-L-lyxo-hexopyranosyl)oxy]-8-ethyl-7,8,9,10-tetrahydro-1,6,8,11-tetrahydroxy-5,12-naphthacenedione

Description:

The chemical substance with the name "(8S,10S)-10-[(3-Amino-2,3,6-trideoxy-α-L-lyxo-hexopyranosyl)oxy]-8-ethyl-7,8,9,10-tetrahydro-1,6,8,11-tetrahydroxy-5,12-naphthacenedione" and CAS number "76034-18-9" is a complex organic compound characterized by its unique structural features. It contains a naphthacenedione core, which is a polycyclic aromatic compound known for its potential biological activity. The presence of multiple hydroxyl groups indicates that it may exhibit significant solubility in polar solvents and could participate in hydrogen bonding interactions. The attached sugar moiety, specifically a trideoxy-hexopyranosyl unit, suggests that this compound may have glycosidic properties, potentially influencing its biological interactions and pharmacological profile. The stereochemistry indicated by the (8S,10S) configuration implies specific spatial arrangements that could affect the compound's reactivity and interactions with biological targets. Overall, this compound may be of interest in medicinal chemistry and biochemistry due to its structural complexity and potential bioactivity.

Formula: C₂₆H₂₉NO₉

InChI: InChI=1/C26H29NO9/c1-3-26(34)8-12-18(15(9-26)36-16-7-13(27)21(29)10(2)35-16)25(33)20-19(23(12)31)22(30)11-5-4-6-14(28)17(11)24(20)32/h4-6,10,13,15-16,21,28-29,31,33-34H,3,7-9,27H2,1-2H3/t10-,13-,15-,16-,21+,26-/m0/s1

InChI key: InChIKey=UHYFCDBUKBJSFA-JYFLSIMMSA-N

SMILES: O([C@@H]1C2=C(C(O)=C3C(=C2O)C(=O)C=4C(C3=O)=CC=CC4O)C[C@](CC)(O)C1)[C@H]5C[C@H](N)[C@H](O)[C@H](C)O5

Synonyms:

• (8S,10S)-10-[(3-Amino-2,3,6-trideoxy-α-<span class="text-smallcaps">L</span>-lyxo-hexopyranosyl)oxy]-8-ethyl-7,8,9,10-tetrahydro-1,6,8,11-tetrahydroxy-5,12-naphthacenedione
• 13-Deoxycarminomycin
• 5,12-Naphthacenedione, 10-[(3-amino-2,3,6-trideoxy-α-<span class="text-smallcaps">L</span>-lyxo-hexopyranosyl)oxy]-8-ethyl-7,8,9,10-tetrahydro-1,6,8,11-tetrahydroxy-, (8S,10S)-
• 5,12-Naphthacenedione, 7,8,9,10-tetrahydro-10-((3-amino-2,3,6-trideoxy-alpha-L-lyxo-hexopyranosyl)oxy)-8-ethyl-1,6,8,11-tetrahydroxy-, (8S-cis)-
• Antibiotic D 788-11
• R 20X
• 5,12-Naphthacenedione, 10-[(3-amino-2,3,6-trideoxy-α-L-lyxo-hexopyranosyl)oxy]-8-ethyl-7,8,9,10-tetrahydro-1,6,8,11-tetrahydroxy-, (8S,10S)-
• (8S,10S)-10-[(3-Amino-2,3,6-trideoxy-α-L-lyxo-hexopyranosyl)oxy]-8-ethyl-7,8,9,10-tetrahydro-1,6,8,11-tetrahydroxy-5,12-naphthacenedione
• (8S)-10α-[(3-Amino-2,3,6-trideoxy-α-L-lyxo-hexopyranosyl)oxy]-8-ethyl-7,8,9,10-tetrahydro-1,6,8α,11-tetrahydroxy-5,12-naphthacenedione
• D-788-11
• 13-Deoxocarminomycin
• Daunorubicin Impurity 4

13-Deoxycarminomycin

CAS: 76034-18-9

13-Deoxycarminomycin is an antitumor antibiotic.

Formula: C₂₆H₂₉NO₉

Purity: 98%

Color and Shape: Solid

Molecular weight: 499.51

Ref: TM-T24968

13-Deoxycarminomycin

Controlled Product

CAS: 76034-18-9

Applications 13-Deoxycarminomycin is used as antitumor agents in preparation of 3'-Deamino-3'-(2"-pyrroline-1"-yl)-5-imine-13-deoxyanthracyclines. 13-Deoxycarminomycin is a doxA gene confers on the transformed host the ability to convert Daunomycin and 13-Dihydrodaunomycin to Doxorubicin.
References Olson, R., et al.: PCT Int. Appl., (2018); Strohl, W., et al.: PCT Int. Appl., (1997);

Formula: C₂₆H₂₉NO₉

Color and Shape: Neat

Molecular weight: 499.51

Ref: TR-D760340

13-Deoxycarminomycin

CAS: 76034-18-9

Formula: C₂₆H₂₉NO₉

Molecular weight: 499.52

Ref: ST-EA-CP-D104012

13-Deoxocarminomycin

CAS: 76034-18-9

Formula: C₂₆H₂₉NO₉

Molecular weight: 499.52

Ref: 4Z-C-302002