CAS 76054-81-4

Thymidine,3'-O-[bis(4-methoxyphenyl)phenylmethyl]-

Description:

Thymidine, 3'-O-[bis(4-methoxyphenyl)phenylmethyl]- is a modified nucleoside derivative of thymidine, which is one of the four nucleosides that make up DNA. This compound features a 3'-O-substituent that includes a bis(4-methoxyphenyl)phenylmethyl group, indicating the presence of methoxy groups that enhance its lipophilicity and potentially influence its biological activity. The presence of aromatic rings suggests that it may exhibit interesting electronic properties and could interact with various biological targets, such as enzymes or receptors. Thymidine derivatives are often studied for their potential applications in antiviral therapies, particularly in the context of DNA synthesis inhibition. The specific structural modifications in this compound may also affect its solubility, stability, and cellular uptake, making it a subject of interest in medicinal chemistry and drug design. As with many nucleoside analogs, understanding its pharmacokinetics and pharmacodynamics is crucial for evaluating its therapeutic potential.

Formula: C₃₁H₃₂N₂O₇

Synonyms:

• 3'-O-(4,4'-Dimethoxytrityl)thymidine
• 3'-O-(Di-p-methoxytrityl)thymidine
• 3'-O-Dimethoxytritylthymidine
• 3'-O-DMT-thymidine
• 3-O-DMTr-DEOXY-THYMIDINE
• 3'-O-DMT-dT
• 3’-O-DMTr?trymidine
• Thymidine, 3'-O-[bis(4-methoxyphenyl)phenylmethyl]-
• 3'-O-DMT-2'-deoxythymidine

1-((2R,4S,5R)-4-(Bis(4-methoxyphenyl)(phenyl)methoxy)-5-(hydroxymethyl)tetrahydrofuran-2-yl)-5-methylpyrimidine-2,4(1H,3H)-dione

CAS: 76054-81-4

1-((2R,4S,5R)-4-(Bis(4-methoxyphenyl)(phenyl)methoxy)-5-(hydroxymethyl)tetrahydrofuran-2-yl)-5-methylpyrimidine-2,4(1H,3H)-dione

Purity: 97%

Molecular weight: 544.6g/mol

Ref: 54-OR1054616

3'-O-DMT-thymidine

Controlled Product

CAS: 76054-81-4

Formula: C₃₁H₃₂N₂O₇

Color and Shape: Off-White To Light Yellow

Molecular weight: 544.595

Ref: TR-O211355

3'-O-DMT-thymidine

CAS: 76054-81-4

3'-O-DMT-thymidine is a nucleoside analogue that is synthesized from thymidine. It has been shown to bind to the proviral dna of HIV and inhibit viral replication when present in a complex with the other nucleosides. 3'-O-DMT-thymidine is also stable at high temperatures and binds to carboxamide groups on proteins. This compound has been shown to be effective as a binder for surfaces and membranes, which may be due to its ability to form stable complexes with terminal phosphates. The stability of these complexes can be influenced by the presence of denaturants such as temperature, pH, or ionic strength parameters. 3'-O-DMT-thymidine also forms stable complexes with linkers that are sensitive to thermal denaturation.

Formula: C₃₁H₃₂N₂O₇

Purity: Min. 95%

Molecular weight: 544.6 g/mol

Ref: 3D-ND06918