CAS 76081-98-6

2-Methyl-8-benzyloxyimidazo[1,2-a]pyridine-3-acetonitrile

Description:

2-Methyl-8-benzyloxyimidazo[1,2-a]pyridine-3-acetonitrile, identified by its CAS number 76081-98-6, is a chemical compound that belongs to the class of imidazopyridines. This substance features a complex structure characterized by a pyridine ring fused with an imidazole moiety, which is further substituted with a methyl group and a benzyloxy group. The presence of the acetonitrile functional group contributes to its reactivity and potential applications in organic synthesis. Typically, compounds of this nature exhibit biological activity, making them of interest in medicinal chemistry and drug development. The molecular structure suggests potential interactions with biological targets, which may lead to pharmacological effects. Additionally, the compound's solubility, stability, and reactivity can vary based on environmental conditions and the presence of other chemical species. As with many organic compounds, safety data and handling precautions should be considered, particularly regarding toxicity and environmental impact. Overall, 2-Methyl-8-benzyloxyimidazo[1,2-a]pyridine-3-acetonitrile represents a significant compound for research and development in various chemical and pharmaceutical applications.

Formula: C₁₇H₁₅N₃O

InChI: InChI=1/C17H15N3O/c1-13-15(9-10-18)20-11-5-8-16(17(20)19-13)21-12-14-6-3-2-4-7-14/h2-8,11H,9,12H2,1H3

SMILES: Cc1c(CC#N)n2cccc(c2n1)OCc1ccccc1

Synonyms:

• Sch-28080
• 2-Methyl-8-(phenylmethoxy)imidazo[1,2-a]pyridine-3-acetonitrile
• [8-(Benzyloxy)-2-Methylimidazo[1,2-A]Pyridin-3-Yl]Acetonitrile
• S28080
• Schering compound 28080
• Imidazo(1,2-A)pyridine-3-acetonitrile, 2-methyl-8-(phenylmethoxy)-
• 2-Methyl-8-(phenylmethoxy)imidazo-(1-2-A)pyrine-3-acetonitrile
• 3-(CYANOMETHYL)-2-METHYL-8-(PHENYLMETHOXY)IMIDAZO[1,2-ALPHA]PYRIDINE
• imidazo-(1-2-a)pyrine-3-acetonitrile

2-Methyl-8-(phenylmethoxy)imidazo[1,2-a]pyridine-3-acetonitrile

CAS: 76081-98-6

Formula: C₁₇H₁₅N₃O

Purity: 98%

Molecular weight: 277.3205

Ref: IN-DA00G2EO

SCH28080

CAS: 76081-98-6

SCH28080

Purity: ≥95%

Molecular weight: 277.32g/mol

Ref: 54-BUP05013

SCH-28080

CAS: 76081-98-6

Formula: C₁₇H₁₅N₃O

Molecular weight: 277.32

Ref: 7W-GL0641

SCH 28080

Controlled Product

CAS: 76081-98-6

Formula: C₁₇H₁₅N₃O

Color and Shape: Neat

Molecular weight: 277.32

Ref: TR-S200033

SCH 28080

CAS: 76081-98-6

SCH 28080 is a potent inhibitor of transcriptional activator protein-1 (AP-1) and nuclear factor-κB (NF-κB). These two transcriptional regulatory proteins are activated by various stimuli, including inflammatory cytokines, such as IL-1β, TNF-α, and IL-6. Activation of these transcription factors leads to the upregulation of the genes encoding proinflammatory mediators, such as eosinophil cationic protein and interleukins. SCH 28080 has been shown to inhibit NF-κB activation in human HL60 cells, which may be due to its ability to bind to both the α subunit of NF-κB and AP-1.

Formula: C₁₇H₁₅N₃O

Purity: Min. 95%

Molecular weight: 277.33 g/mol

Ref: 3D-BDA08198

SCH28080

CAS: 76081-98-6

SCH28080 is a reversible and K+-competitive inhibitor of gastric H+/K+-ATPase with an IC50 value of 20 nM (rabbit microsomal membrane).SCH28080 is a potent

Formula: C₁₇H₁₅N₃O

Purity: 99.24%

Color and Shape: Solid

Molecular weight: 277.32

Ref: TM-T16865