CAS 760952-64-5

Mal-PEG1-acid

Description:

Mal-PEG1-acid, also known as Maleimide-Polyethylene Glycol (PEG) acid, is a chemical compound characterized by its functional groups and polymeric structure. It features a maleimide group, which is reactive towards thiols, making it useful in bioconjugation and drug delivery applications. The polyethylene glycol (PEG) segment provides hydrophilicity, enhancing solubility in aqueous environments and improving the pharmacokinetic properties of conjugated molecules. The presence of the carboxylic acid group allows for further functionalization and conjugation with other biomolecules, facilitating the development of targeted therapies and diagnostic agents. Mal-PEG1-acid is typically utilized in the synthesis of bioconjugates, including proteins, peptides, and nucleic acids, due to its ability to form stable linkages. Its properties, such as low toxicity and biocompatibility, make it a valuable tool in pharmaceutical and biomedical research. Overall, Mal-PEG1-acid serves as an important building block in the design of advanced therapeutic systems.

Formula: C₉H₁₁NO₅

Synonyms:

• Mal-PEG1-acid
• 3-[2-(2,5-Dioxo-2,5-dihydro-1h-pyrrol-1-yl)ethoxy]propanoic acid
• Mal-PEG1-CH2CH2COOH

Propanoic acid, 3-[2-(2,5-dihydro-2,5-dioxo-1H-pyrrol-1-yl)ethoxy]-

CAS: 760952-64-5

Formula: C₉H₁₁NO₅

Purity: 98%

Color and Shape: Solid

Molecular weight: 213.1873

Ref: IN-DA00ICPA

Mal-PEG1-acid

CAS: 760952-64-5

Mal-PEG1-acid

Purity: 95%

Molecular weight: 213.19g/mol

Ref: 54-BIPG1491

Propanoic acid, 3-[2-(2,5-dihydro-2,5-dioxo-1H-pyrrol-1-yl)ethoxy]-

CAS: 760952-64-5

Purity: 98%

Color and Shape: Solid

Molecular weight: 213.1889954

Ref: 10-F863933

Mal-PEG1-acid

CAS: 760952-64-5

Mal-PEG1-acid is a PEG compound with two different functional groups (also known as heterobifunctional). Unlike homobifunctional PEG compounds (same functional group on both ends), this type of compounds are more versatile as have two different anchor points. Mal-PEG1-acid is used as a linker and spacer to add a PEG moiety, via pegylation (a bioconjugation technique) to proteins, peptides, oligonucleotides, small molecules and nanoparticles.

Formula: C₉H₁₁NO₅

Purity: Min. 95%

Molecular weight: 213.18 g/mol

Ref: 3D-KFB95264

Mal-PEG1-acid

CAS: 760952-64-5

Mal-PEG1-acid is a non-cleavable (1 unit PEG) ADC linker used in the synthesis of antibody-drug conjugates (ADCs)

Formula: C₉H₁₁NO₅

Purity: 98%

Color and Shape: Solid

Molecular weight: 213.19

Ref: TM-T15973